Drug family: Antiandrogen
This drug is a generic of ANDROCUR
WHAT IS CYPROTERONE ACETATE TEVA PRESCRIBED FOR?
This medicine contains a derivative of progesterone . It has an antihormonal action: it opposes the action of androgen hormones , essentially testosterone . In men, its action slows down the growth of prostate cells .
prostate cancer ; _ _
certain forms of paraphilia, in association with psychotherapeutic treatment.
PRESENTATIONS OF THE DRUG CYPROTERONE ACETATE TEVA
COMPOSITION OF THE DRUG CYPROTERONE ACETATE TEVA
| p cp | |
| Cyproterone acetate | 100mg |
| Lactose | + |
CONTRAINDICATIONS OF THE DRUG CYPROTERONE ACETATE TEVA
severe liver disease, certain rare diseases causing excess bilirubin in the blood;
tuberculosis or deterioration in general condition linked to a serious illness;
thromboembolic accident ( phlebitis , pulmonary embolism, myocardial infarction , etc.) old or occurring during treatment;
severe depression ;
sickle cell anemia ;
presence of an old or recent meningioma ( brain tumor ).
ATTENTION
This medication can, in high doses, be responsible for sometimes serious liver damage. A liver test is usually ordered before starting treatment. Immediately report to your doctor any symptom that could lead to fear of a toxic effect on the liver: persistent abdominal pain, loss of appetite, dark urine, intense itching, jaundice. Analyzes may be necessary to ensure the absence of anomaly.
Medical monitoring should be reinforced in the event of diabetes or chronic liver disease.
Thromboembolic accidents have been reported during treatment: in the event of the occurrence of significant and unusual headaches, visual disturbances or increased blood pressure , seek prompt medical advice.
Studies have shown a marked increase in the risk of occurrence of meningioma ( most often benign brain tumour ) in patients treated with cyproterone acetate at high doses over a long period. The duration of treatment should be as short as possible and the dose used as low as possible. A search for meningioma by brain imaging ( MRI ) must be carried out at the start of treatment, then regularly if the treatment is continued for several years. If a meningioma is diagnosed, treatment should be permanently discontinued. An information sheet will be given to you by the doctor at the time of the prescription.
If you must drive or use a dangerous machine, make sure beforehand that this medicine does not affect your alertness .
INTERACTIONS OF THE DRUG CYPROTERONE ACETATE TEVA WITH OTHER SUBSTANCES
This medication may interact with herbal products containing St. John's wort and medications containing perampanel,
Also tell your doctor or pharmacist if you are taking a medicine containing any of the following: carbamazepine, fosphenytoin, phenobarbital, phenytoin, primidone, oxcarbazepine, rifabutin, rifampicin, nevirapine, efavirenz, dabrafenib and enzalutamide.
INSTRUCTIONS FOR USE AND DOSAGE OF THE DRUG CYPROTERONE ACETATE TEVA
This medication should be swallowed with a glass of water.
USUAL DOSE:
Prostate cancer : 2 to 3 tablets at 100 mg per day, in 2 or 3 doses.
Reduction of sexual urges: the dosage is individual.
TIPS
Specific delivery conditions :
To obtain this medicine, an information certificate on the risk of meningioma, signed by the patient and his doctor, must be presented to the pharmacist at the same time as the prescription. This certificate is valid for one year, and must therefore be renewed each year if the treatment is continued.
POSSIBLE SIDE EFFECTS OF THE DRUG CYPROTERONE ACETATE TEVA
Decreased sperm production usually reversible upon discontinuation of treatment, which may result in temporary sterility.
Gynecomastia , impotence , low libido, sweating, hot flushes, anemia .
Change in weight, shortness of breath, heavy legs, migraine , headache, rash , fatigue, restlessness and depression .
Bone loss in case of prolonged treatment.
Rarely: hepatitis , thromboembolic accident, meningioma (which may result in various symptoms such as frequent headaches, vision, language, memory and hearing disorders, nausea, dizziness , convulsions , loss of smell , weakness, paralysis ).
