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THE LESCUYER LABORATORY OBTAINS A COMPLETELY NEW POSITIVE OPINION FROM THE EFSA FOR A FOOD SUPPLEMENT

THE LESCUYER LABORATORY OBTAINS A COMPLETELY NEW POSITIVE OPINION FROM THE EFSA FOR A FOOD SUPPLEMENT:

The European market is going through a historic moment since to date, no food supplement has managed to obtain a favorable opinion for such a request for a claim. The LESCUYER Laboratory is therefore to this day a pioneer.

A unique proof of effectiveness recognized by a demanding authority:

Obtaining EFSA recognition is a long process. Indeed, the EFSA (European Food Safety Authority) is not only the highest European authority on food safety, but it is also one of the most demanding panels of nutrition experts in the world. A positive opinion from EFSA is therefore equivalent to the highest possible scientific recognition at European level.

With its positive opinion, the EFSA now scientifically recognizes the health benefits of LIMICOL: LIMICOL "reduces the blood level of LDL-cholesterol. A high level of LDL-cholesterol is a risk factor for the development of coronary heart disease ".

An unprecedented and exclusive claim:

It is the first food supplement to benefit from data protection for a claim relating to the reduction of a disease risk factor . Upon final approval from the European Commission, Laboratoire LESCUYER will therefore be the only one able to claim this health claim on its exclusive and patented formula.

A scientific requirement that deserves this recognition:

Obtaining this positive opinion is the fruit of 5 years of research which made it possible to submit a very complete scientific file to the EFSA, including, among other things, the results of 3 proprietary clinical studies .

The medical-scientific team of Laboratoire LESCUYER has surrounded itself with external collaborators (biochemists, clinicians, toxicologists, biostatisticians) to bring together all the documents in the claim application file. Independent research groups conducted the 3 clinical trials with the highest level of scientific rigor : randomized, double-blind, placebo-controlled studies carried out on a total of 184 volunteers. These studies 2,3,4 have all been published in international scientific journals, a guarantee of the seriousness of the results advanced.

Thanks to this research work, LEMICOL is today the only exclusive and patented dietary supplement, with its effectiveness officially recognized by Europe.

About LIMICOL:

Marketed in 2008 , LEMICOL is a dietary supplement that combines plant extracts, red yeast rice and vitamins, a total of 8 active ingredients that act in synergy to naturally reduce excess cholesterol.

The LIMICOL formula contains Artichoke extract, red yeast rice, sugar cane policosanols, garlic extract, maritime pine bark OPCs, as well as vitamins B2, B3 and E.

Effectiveness proven by 3 clinical studies:

The effectiveness of LEMICOL on lowering cholesterol has been demonstrated by 3 clinical studies conducted on a total of 184 volunteers with excess cholesterol. From the 1st month, the daily intake of 3 tablets of LEMICOL significantly reduces the total cholesterol level by 15.3%², the LDL-cholesterol level by 21.4%² and the blood cholesterol level by 15.4%³. of Apo-B. These markers are then stabilized over the following 3 months. After 4 months of supplementation, there is also a decrease of 12.2%² in triglycerides.

The guarantee of high tolerance:

The effectiveness and uniqueness of the LEMICOL formula are based on the synergistic action of the active ingredients selected and on the precise dosage of each ingredient. The LESCUYER Laboratory has voluntarily chosen to incorporate monacolin K (active substance derived from red yeast rice) up to 2 mg per recommended daily dose, while maintaining perfect efficacy. This dosage, lower than the recommended doses, makes it possible to avoid the muscular discomfort generally observed , linked to the consumption of red yeast rice.

The excellent tolerance of LEMICOL has been confirmed by 3 clinical studies.

About the LESCUYER Laboratory:

Laboratoire LESCUYER, an expert in micronutrition, is a major player in the French market for food supplements, founded in 1994 by Doctor Jean-François LESCUYER. The Laboratory specializes in the formulation and marketing of very high quality food supplements. With 75 products and more than 100 references, it offers many ranges aimed at preserving and improving health capital. At the forefront of scientific research, the company is committed to developing innovative, effective and safe health products, widely recognized and recommended by many health professionals.

HYPERCHOLESTEROLEMIA:

In France, nearly 20% of the adult population has hypercholesterolemia, ie an excess of cholesterol in the blood. How to control your cholesterol level? Answers.

Hypercholesterolemia corresponds to a total cholesterol level that is too high in the blood compared to the limit recommended by medical authorities. It is then necessary to change your habits to lower the rate and it is best to consult your doctor.

What is cholesterol?

Cholesterol is a fat (or lipid) that circulates in the blood. Two-thirds of it is made by the liver from protein, fatty acids and carbohydrates. We then speak of endogenous origin.

The final third comes from the animal foods we eat such as meat, poultry, fish, eggs and dairy products. We then speak of exogenous origin.

Cholesterol plays several major roles in the body: it participates in the production of cell membranes, contributes to the production of many hormones such as testosterone and estrogen. It synthesizes vitamin D , helps the liver to manufacture the bile acids essential for the digestion of dietary fats and it also participates in the proper functioning of the nervous system.

Cholesterol is therefore essential for the proper functioning of our body. Everything lies in the balance between "good" and "bad" cholesterol in our body: an excess of "bad" cholesterol compared to "good" cholesterol can jeopardize our cardiovascular health and ultimately increase the risk of disorders. cardiovascular.

Good and bad cholesterol: how to tell them apart?

Insoluble in the blood and composed mainly of water, cholesterol needs vehicles, called "carriers", to reach the various organs. There are two types, low density lipoproteins (VLDL and LDL) and high density lipoproteins (HDL). The first correspond to the "bad" and the second, to the "good" cholesterol.

VLDL and LDL or “bad cholesterol”:

Composed of cholesterol and triglycerides (another form of lipid), lipoproteins called VLDL carry cholesterol on the go. The whole leaves the liver, where it is produced, in the form of "clusters" whose size is reduced as they release into the blood, triglyceride fats used as fuel by the cells. Triglycerides are stored in fatty tissue, where they constitute an energy reserve, and in the muscles to be burned during physical activity. Once rid of triglycerides, VLDL transporters become LDL, whose role this time is to transport cholesterol to the cells that need it. They are the ones that contain the highest concentration of cholesterol and are called “bad” cholesterol.

HDL or “good cholesterol”:

HDLs are the return path carriers. They owe their name of “good” cholesterol to the fact that they help to recover the superfluous bad cholesterol, stuck to the walls of the arteries. Cholesterol is transported to the liver where it is transformed and then eliminated. HDLs therefore protect the arteries by preventing them from becoming clogged.

Hypercholesterolemia: what is it?

Hypercholesterolemia is when the level of total cholesterol in the blood is too high . If the liver produces too much cholesterol or if the food provides too much, the excess is deposited in the tissues and on the walls of the blood vessels where it then contributes to form thick and hard deposits, called atherosclerotic plaques. These plaques are due to oxidized LDL-cholesterol. The arteries gradually clog and become less flexible.

Hypercholesterolemia is often accompanied by elevated blood triglyceride levels. These fats are produced by the liver and provided by food (especially sugars and alcohol). They are stored in the fatty tissue of the human body and represent the body's largest energy reserve. A high level of triglycerides in the blood increases the risk of occurrence of

How does hypercholesterolemia manifest?

There is no warning sign to know if you are affected by hypercholesterolemia. It is possible to have too much cholesterol, and still feel great. In the majority of cases, hypercholesterolemia is discovered too late, when cardiovascular disorders appear.

Hence the importance of regularly checking your cholesterol level. The right rhythm? Every 5 years, from age 40 for men and from age 50 for women.

To know your cholesterol level, a blood test is enough. The lipid profile indicates the complete dosage of all the fats in the blood: the total cholesterol level, the LDL ("bad" cholesterol), the HDL ("good" cholesterol) and the triglycerides. The dosage is indicated in mmol per liter of blood or in g/l

What are the causes of hypercholesterolemia?

In general, high cholesterol is the result of a diet that is too high in fat.

However, other parameters may be involved: genetics (we then speak of familial hypercholesterolemia), certain diseases such as type 2 diabetes, family lifestyle habits, the intake of synthetic hormones or certain medications, in particular those used against high blood pressure.

Certain factors such as stress, smoking and obesity can also make high cholesterol worse.

How to lower your cholesterol level?

A healthy diet low in saturated fat:

The first objective is to lower the level of bad cholesterol by monitoring the quantity and nature of the fats consumed. In small amounts, some fats are beneficial to health. Others, on the other hand, are much less so. This is the case of fats found in foods of animal origin (charcuterie, cheese), in industrial sweet preparations or in palm oil. It is advisable to favor vegetable fats such as olive or rapeseed oil. It is also recommended to give pride of place to cholesterol-lowering foods such as fruits and vegetables, legumes and whole grains. These sources of fiber make it possible to capture cholesterol and eliminate part of it in the stool.

Regular physical activity:

Combined with a healthy and balanced diet, physical activity is a pillar of cholesterol balance. Sport acts as a consumer of cholesterol and participates in the use of fat as muscle fuel. The simplest activities like walking or swimming are very effective, the most important being regularity.

FOCUS ON RED YEAST RICE:

Red yeast rice is a microscopic fungus grown on rice and native to Asia, rich in monacolin. Red yeast rice is also an active ingredient that has recently been the subject of much controversy for three reasons:

It may contain a mycotoxin called citrinin:

Always concerned to offer you effective and safe products, the LESCUYER Laboratory has all the batches of red yeast rice used in the composition of LEMICOL analyzed using an ultra-sensitive analysis method. We can thus guarantee you the total absence of citrinin in LEMICOL.

It can cause the same inconveniences as statins:

Red yeast rice contains monacolin K, an active substance which can, at high doses, cause muscle, liver or kidney discomfort. Thanks to the association and the synergy of action of the active ingredients of LIMICOL, Laboratoire LESCUYER has succeeded in offering you a product with scientifically proven efficacy, containing a low dose of monacolin K. The 3 LIMICOL clinical studies have confirmed the total absence of discomfort and guaranteed excellent tolerance of this cholesterol complex.

The EFSA* concludes that an effect on cholesterol cannot be guaranteed below 10 mg of monacolin K per day.

The effectiveness and uniqueness of the LEMICOL formula are based on the synergistic action of the active ingredients selected and on the precise dosage of each ingredient. The LESCUYER Laboratory has voluntarily chosen to incorporate monacolin K at a level of 2 mg per recommended daily dose to limit the discomfort generally observed while maintaining perfect efficacy (Efficacy of LIMICOL confirmed by the positive opinion of the EFSA) .

NATURAL SOLUTIONS TO LOWER ITS LEVEL

Between good and bad cholesterol, food supplements based on active ingredients such as red yeast rice can be effective in reducing the bad rate.

Cholesterol is a natural lipid that your body needs. However, it is recommended to regularly check its level. In case of excess, discover all the natural solutions to lower it effectively.

Cholesterol is a lipid molecule, in other words a fatty molecule. It is naturally produced by the body and is essential for its proper functioning. Cholesterol plays two main roles in your body: structural on the one hand and functional on the other. " It enters into the composition of cell membranes and participates in the production of certain elements of the body such as vitamin D, corticosteroids, sex hormones ", explains Nathalie Ballesteros, doctor of pharmacy at Laboratoire Lescuyer.

Where do good and bad cholesterol come from?

HDL cholesterol is called “good cholesterol”. It circulates in the body, from the cells to the liver by attaching itself to molecules called “high density lipoproteins”. These evacuate the cholesterol deposit in the arteries: they are indeed responsible for bringing the excess to the liver so that it is eliminated.

It is recommended to have an HDL cholesterol level greater than 0.4 g/l in the blood.

" LDL cholesterol is characterized as 'bad cholesterol' because it is transported from the liver to other target tissue cells ", continues Nathalie Ballesteros. In excess, it accumulates on the arterial walls, increasing the risk of cardiovascular disorders . It is recommended to maintain an LDL cholesterol level below 1.6 g/l in the blood, in the absence of risk factors.

What are the solutions to quickly lower your cholesterol level?

Cholesterol is essential for the proper functioning of the body. However, it is advisable not to exceed an overall cholesterol level of 2 grams per liter of blood, in the absence of risk factor. Too high a level of "bad cholesterol" (LDL) is generally the direct result of a poor lifestyle, unbalanced eating habits and especially endogenous cholesterol (produced by the body).

Making the right food choices can already effectively lower your cholesterol level.

High cholesterol: foods to avoid

It is important to reduce as much as possible the consumption of saturated fats found in cold meats, cheeses, butter, meats, peanut/palm oils or in pastries.

Preferred diet

In case of excess bad cholesterol, a specific diet is required. Give pride of place to the fibers that you find in quantity in fruits and vegetables, legumes and whole grains.

By binding to cholesterol in the intestine, fiber facilitates its natural elimination. Consumed several times a week on a regular basis, they can even lead to a 5% drop in LDL cholesterol.

The best sources of monounsaturated fats :

olive oil, rapeseed, hazelnut
walnuts, hazelnuts, almonds...
lawyer
fiber (cooked oat bran, soybeans, mango, grapefruit...

Red yeast rice is an effective active ingredient in maintaining normal cholesterol levels in the blood. You can find this ingredient easily in some dietary supplements .

Think of omega 3 (in fat possions) because they contribute to cardiovascular balance. Studies have shown that eating fish once or twice a week reduces cardiovascular disorders.

To effectively and safely lower your cholesterol levels, however, it is particularly advisable to discuss the correct course of action with your doctor. Anti-cholesterol treatment is systematically associated with a diet.

Seasonal vegetables

Carrots are one of the most consumed vegetables in France. Some studies highlight the benefits of this vegetable on blood cholesterol levels. The consumption of carrots in animals would also increase antioxidant status and vitamin E levels in the blood, in addition to reducing cholesterol and triglycerides in the liver and in the blood 1 . Cabbage and garlic are also seasonal vegetables to add to your plates. Used as a condiment, garlic is easily added to your culinary preparations but to benefit from all its virtues, it is better to eat it raw. Garlic has been the subject of numerous studies, showing that consuming garlic can help maintain normal cholesterol levels.2 .

Seasonal fruits

There are many varieties of apples , especially at this time of year. You can eat them raw or cooked, as a dessert, as a snack, in salads or even as an accompaniment with, for example, chicken or duck. According to a study published in the Journal of Nutrition, regular consumption of apples would help maintain cardiovascular balance and reduce the absorption of cholesterol and lipids in the intestines 3 . Just like the apple, the pear is a seasonal fruit to favor because it is very rich in soluble fibers which immobilize cholesterol and promote its intestinal elimination 4 . From November, clementines and mandarinsquickly make their place in the daily life of the French. Easy to transport, they are also tasty and rich in vitamins. Also, a study conducted among women revealed that regular consumption of mandarins during the winter would positively influence the lipid balance 5 .

oilseeds

Walnuts and hazelnuts are oleaginous dried fruits, whose peak season is between mid-September and late November . They are rich in unsaturated fats which help maintain normal cardiovascular balance, and in active nutrients such as fibre, minerals, vitamin E and polyphenols. Regular consumption of nuts can help maintain normal cholesterol levels 6 .

The 6 hygiene and dietary advice to adopt on a daily basis

To support you in your micronutritional approach, the LESCUYER Laboratory offers you 6 hygiene and dietary advice in particular:

Reduce the consumption of foods rich in saturated fatty acids.

Promote the intake of unsaturated fatty acids.

Choose foods that are sources of fiber.

Raise your antioxidant status.

Watch your salt intake.

Adopt simple cooking techniques.