Showing posts with label insulin resistance. Show all posts
Showing posts with label insulin resistance. Show all posts

Drugs interact with insulin.. An increase or decrease in the level of sugar in the blood

Drugs interact with insulin:

Some medicines that are used for other conditions such as high blood pressure, COPD, or depression can affect your blood sugar. Some over the counter medicines can affect your blood sugar. Alcohol, caffeine and nicotine all affect your blood sugar.

Below are lists of some of the medicines that might cause your blood sugar to increase or decrease. Do not stop taking prescription medicines or change the dose without talking to your doctor. Always let your doctor know what over the counter medicines, vitamins and supplements you take.

Medicines That Increase Blood Sugar:

  • Alcohol (acute use-social drinking).
  • Antibiotics (Dapsone, Rifampin).
  • Antidepressants (Zyprexa, risperdal, Clozaril, Seroquel, Abilify, Geodon, lithium).
  • Beta-2 stimulators (Proventil, Alupent, Serevent, Foradil, Brethine, Theo-Dur).
  • Caffeine.
  • Corticosteroids (Prednisone, Decadron, DepoMedrol).
  • Dilantin (phenytoin).
  • Nicotine (smoking and patches).
  • Estrogens (Premarin, hormone replacement therapy).
  • Heart and blood pressure medications (amiodarone, beta blockers, calcium channel blockers, catapress, diuretics).
  • Oral contraceptives (Birth control pills).
  • Niacin or nicotinic acid.
  • Protease inhibitors (ritonavir etc-AIDS drugs).
  • Thyroid hormones (Synthroid, Levothroid).

Medicines That Decrease Blood Sugar:

  • Antibiotics (Bactrim/Septra).
  • Alcohol (acute excess amounts).
  • Aspirin and other salicylates in larger doses.
  • Heart and blood pressure medications (ACE inhibitors, beta blockers, Norpace, Quinidine)
  • Quinine.
  • Tylenol (acetaminophen-especially in larger doses).

Insulin resistance.. Raise the level of sugar in the blood by producing glucose from the liver and reduce inventory glucose enter cells

Insulin resistance

Intended insulin resistance if treatment requires the patient to use a larger dose of 200 units of insulin a day to control blood sugar and prevent coma sugar Ketone. Most patients who are treated insulin arises to have the amount of anti-immune IgG MDR, which is equivalent to the effect of insulin to a low degree. In some diabetics, especially those who have a degree of tissue due to insulin sensitivity such as that occurring in obese diabetics, as well as patients who use insulin intermittently using preparations of insulin cow is pure former would receive their high-caliber High titre Of anti immune IgG Resistant to insulin. This leads to increased need for larger doses of insulin is often greater than 200 units per day.With the development of insulin purification, such side effect became rare.

In the event of resistance to a particular type of insulin suddenly it must make sure that never expires insulin or presence of inflammatory satisfactory. It is known that during the stage sick there is stress to the patient resulting in an increase in the secretion and the concentration of hormones anti-insulin (glucagon and Abienkerin, and cortisol and growth hormone), which lead to higher blood sugar levels by producing glucose from the inventory of the liver and reduce the entry of glucose into cells.

Reasons for the ineffectiveness of insulin.. Antibodies to insulin. Lack of effectiveness of insulin

Reasons for the ineffectiveness of insulin

There are certain reasons lead to the lack of response from diabetic insulin for treatment in some cases, including:

  • Injury to any microbe, as the microbes reduce the resistance of the body and especially the patients who suffer from lack of blood sugar control.
  • Obese diabetic needs to a large dose of insulin.
  • Gigantism's disease, which leads to increased secretion of growth hormone.
  • Various liver diseases which lead to a lack of effectiveness of insulin.
  • Causes immune automatically lead to reduced effectiveness of insulin due to the formation of antibodies to insulin. 
  • Expiration & insulin user.

What is insulin?


Insulin is a hormone responsible for controlling blood glucose levels, as it allows glucose to enter cells to provide us with energy. There are several different types and forms of insulin used medically, as it is prescribed to patients according to their health needs. The main function of insulin used as a treatment is to control the level of glucose (sugar) in the blood in patients with diabetes.
 

Do all diabetics need insulin?


If you are diagnosed with type 1 diabetes, you will be prescribed insulin as the body needs it to control blood glucose levels. Some people with type 2 diabetes also need insulin if their blood glucose cannot be controlled in any other way. Control of blood glucose level is critical as too high or too low a glucose level can result in severe life-threatening symptoms.
 

How is insulin used?


You will be given instructions on the use of insulin by your diabetes team, and you will be provided with all necessary information on how to use insulin and how much to take. In general, it can be indicated that the use of insulin is in one of the following ways: syringes, an insulin pen, or an insulin pump.
 

How is insulin transported and stored?

Insulin must be stored in an appropriate manner to ensure its effectiveness, and care must be taken to have the dose you need with you at all times. Tips and recommendations for insulin storage and transportation include:

  • Do not expose insulin to very hot or very cold temperatures
  • Use the temperature control device provided by your diabetes care team when administering insulin
  • Never store insulin in a car or expose it to the sun
  • Insulin should not be kept in the freezer (refrigerator freezer).
  • Check the expiration date on the insulin package, and inspect for any abnormal signs in the package to ensure that it has not been tampered with, leading to damage or spoilage of its contents.
  • Ensure that syringes and needles are stored properly and disposed of in a safe and appropriate manner, as instructed by your diabetes team

What is a major factor in errors related to insulin?

In terms of the forms of insulin administration error, the most common error types were the wrong dose, omitted or delayed insulin. The current common known contributing factors leading to insulin error were transcribing errors, drug calculation mistakes, non-adherence to protocols, and failure in communication.

What are three possible causes of insulin resistance?

Obesity (being significantly overweight and belly fat), an inactive lifestyle, and a diet high in carbohydrates are the primary causes of insulin resistance. Some women develop insulin resistance while they are pregnant. This is called gestational diabetes. Certain diseases are associated with insulin resistance.

Why is insulin important for the body's effective use of glucose?

Insulin helps keep the glucose in your blood within a normal range. It does this by taking glucose out of your bloodstream and moving it into cells throughout your body. The cells then use the glucose for energy and store the excess in your liver, muscles, and fat tissue.

Why is insulin ineffective in type 2 diabetes?

In type 2 diabetes, the pancreas makes insulin, but the cells don't respond to it as they should. This is called insulin resistance. When glucose can't get into cells, the blood sugar level rises. Then the pancreas works harder to make even more insulin.

When does insulin become ineffective?

Note: Insulin loses some effectiveness when exposed to extreme temperatures. The longer the exposure to extreme temperatures, the less effective the insulin becomes. This can result in loss of blood glucose control over time.

What factors are associated with insulin resistance not being able to use insulin effectively?

The two main factors that seem to contribute to insulin resistance are excess body fat, especially around your belly, and a lack of physical activity. People who have prediabetes and Type 2 diabetes usually have some level of insulin resistance. People with Type 1 diabetes can also experience insulin resistance.

What happens if you have insulin antibodies?

If you have IgG and IgM antibodies against insulin, your body reacts as if the insulin in your body is a foreign protein that needs to be removed. This may make insulin less effective, or not effective at all. This is because the antibody prevents the insulin from working the right way in your cells.

What makes insulin ineffective?

The pancreas pumps out more insulin to get blood sugar into cells. Over time, cells stop responding to all that insulin—they've become insulin resistant. The pancreas keeps making more insulin to try to make cells respond. Eventually, the pancreas can't keep up, and blood sugar keeps rising.

Drugs lead to high blood sugar.. Cortisone. Drugs to treat high blood pressure. Some bronchodilators

Drugs lead to high blood sugar

There are some medications that can lead to high blood sugar level and therefore better not to use in a diabetic patient.

what is?

  • Cortisone.
  • Niacin or Alnecotiink acid (Ronicol)
  • Some such as diuretics Thiazides
  • Pill containing large amounts of the hormone estrogen Estrogen.
  • Beta inhibitors b-blockers Used to treat high blood pressure.
  • Nifedipine Used in the treatment of high blood pressure.
  • Some bronchodilators such as Salbutamol Used in the treatment of asthma.
  • (Epanutin) Phenytoin
  • Lactulose: Syrup is used to treat constipation in some cases of hepatic dysfunction.
  • Some cough medicines: they contain sugar and perhaps also Cortisone.
Subscribe to: Posts (Atom)