Drug family: Vitamin A
IN WHICH CASE IS THE DRUG A 313 CAPSULE PRESCRIBED?
This medication contains vitamin A, a substance essential for metabolism . Vitamin A deficiency is responsible for impaired night vision and dryness of the skin and mucous membranes .
It is used in the treatment of vitamin A deficiency .
PRESENTATIONS OF THE DRUG A 313 CAPSULE
A 313 : capsule (orange-yellow); box of 30
On prescription (List I) - Reimbursable at 65% - Price: €2.55 .
The prices mentioned do not take into account the pharmacist's " dispensing fees ".
COMPOSITION OF THE DRUG A 313 CAPSULE
p-caps
Retinol ( vitamin A) 50,000 IU
Sorbitol +
Active substances:
retinol palmitate
,
Oily Concentrated Synthetic Retinol
Excipients : Purified water, Cod liver oil, Gelatin, Glycerol, 70% Sorbitol
CONTRAINDICATIONS OF THE DRUG A 313 CAPSULE
This medicine should not be used in the following cases:
lipid absorption disorders,
chronic poor absorption by the digestive tract,
in combination with drugs interfering with the absorption of vitamin A.
Vitamin A deficiencies due to these disorders can only be corrected by injectable vitamin A.
ATTENTION
Vitamin A is present in many medicines, some of which are available in self- medication : avoid combining them with this medicine because an overdose of vitamin A is likely to cause serious adverse effects . Follow the dosage and duration of treatment prescribed by your doctor.
Keep the capsules out of the reach of children.
INTERACTIONS OF THE DRUG A 313 CAPSULE WITH OTHER SUBSTANCES
This medication should not be combined with:
antibiotics of the cyclin family : risk of intracranial hypertension , in the event of vitamin A intake of more than 10,000 IU per day;
retinoids : risk of vitamin A overdose .
FERTILITY, PREGNANCY AND LACTATION
PREGNANCY :
In case of vitamin A deficiency confirmed by the doctor, this medicine can be used during pregnancy.
FEEDING WITH MILK :
This medication passes into breast milk: it is not recommended during breastfeeding without medical advice.
INSTRUCTIONS FOR USE AND DOSAGE OF THE DRUG A 313 CAPSULE
The capsules should be swallowed whole with a glass of water.
USUAL DOSE:
Adult and child over 8 years old : 1 or 2 capsules (50,000 or 100,000 IU ) every 10 days.
Do not renew the cures without the advice of your doctor.
TIPS
The catches are spaced out because the liver ensures the storage of vitamin A between the catches.
Vitamin A is provided by fatty substances: especially fish liver oil, egg yolk, butter and other dairy products . It is also made by the liver from certain foods: vegetables, fruits. A balanced and diversified diet usually provides sufficient amounts of vitamin A.
Store this medication away from light.
POSSIBLE SIDE EFFECTS OF THE DRUG A 313 CAPSULE
The appearance of adverse effects reflects an overdose and requires discontinuation of treatment:
acute poisoning: headaches, loss of appetite, nausea, vomiting, diarrhea , irritability, confusion of ideas, convulsions ;
Accumulation poisoning: headaches, inability to bear light, abnormal bones, painful swelling of the wrists and ankles.
Like all medicines and confectionery containing non-absorbable sugars ( sorbitol , maltitol, etc.), possibility of diarrhea in the event of significant intake.
You have experienced an adverse effect likely to be due to this medication, you can report it online.
What is therapeutic range of a drug?
The therapeutic range of a drug is the dosage range or blood plasma or serum concentration usually expected to achieve the desired therapeutic effect. This does not mean that patients may not achieve benefit at concentrations below the minimum threshold, or may not experience adverse effects if kept within the range.
How do you calculate therapeutic index of a drug?
Therapeutic index is calculated by dividing the toxic dose for 50% of the population by the minimum effective dose for 50% of the population.
What is low therapeutic index?
Introduction. Narrow therapeutic index drugs are drugs where small differences in dose or blood concentration may lead to serious therapeutic failures and/or adverse drug reactions that are life-threatening or result in persistent or significant disability or incapacity.
What is the maximum sentence for conspiracy to supply Class A drugs UK?
For sentencing in the Magistrates' court for conspiracy to supply class A drugs, the maximum sentence can include either a fine of up to a total of £5000, up to 6 months in prison, or both.
What is the maximum sentence for conspiracy to supply Class A drugs?
In Crown Court, the maximum sentence for conspiracy to supply class A drugs can include either or both: An unlimited fine. A prison sentence up to and including life imprisonment.
Do first time drug offenders go to jail UK?
Do first time drug offenders go to jail in the UK? If you are a first-time offender caught in possession of a small amount of Class A drugs for personal use, the good news is that you are unlikely to be sent to jail. You could get an out of court disposal such as a community resolution or a conditional caution.
Is 10 a high therapeutic index?
Conversely, a drug with a narrow TI has generally a steep concentration–response relationship for efficacy, toxicity or both so that there is a narrowly defined range between risk and benefit. It is generally considered that a drug has a good safety profile if its TI exceeds the value of 10.
Is a therapeutic index of 1 GOOD?
A higher therapeutic index is preferable to a lower one: a patient would have to take a much higher dose of such a drug to reach the toxic threshold than the dose taken to elicit the therapeutic effect.
