ACTONEL RANGE OF DRUGS

 Drug family: Bisphosphonate

IN WHICH CASE IS ACTONEL 30 MG PRESCRIBED?

This drug belongs to the family of bisphosphonates. It works by blocking cells that destroy bone and fighting against demineralization.

It is used in the treatment of Paget 's disease .

PRESENTATIONS OF THE DRUG ACTONEL 30 MG

ACTONEL 30 mg  : tablet (oval; white); box of 28

On prescription (List I) - Reimbursable at 65% -  Price:  €188.49 .

The prices mentioned do not take into account the pharmacist's " dispensing fees ".

COMPOSITION OF THE DRUG ACTONEL 30 MG

	share
Risedronate sodium	30 mg

Substance active :Risedronate sodium

Excipients  : Microcrystalline cellulose, Chroma-tone white, Crospovidone, Dri-klear, Hyprolose, Hypromellose, Lactose monohydrate, Macrogol 400, Macrogol 8000, Magnesium stearate, Colloidal anhydrous silica, Titanium dioxide

CONTRAINDICATIONS OF THE DRUG ACTONEL 30 MG

This medicine should not be used in the following cases:

• severe kidney failure ,

• hypocalcemia ,

• pregnancy ,

• breastfeeding .

ATTENTION

Like other bisphosphonates, this medication may be irritating to the mouth or esophagus. It is important :

• not to chew or suck the tablet;

• to take the tablet in a sitting or standing position, with a large glass of water;

• not to lie down within half an hour of taking it.

Tell your doctor if you have digestive problems like heartburn, acidity, or burning behind your breastbone .

Throughout the duration of the treatment, calcium intake is necessary, either through food or through specific joint treatment.

Damage to the jaw bones which can lead to tooth loss has been reported in some people taking bisphosphonates. A dental examination and preventive care may be necessary before starting treatment, especially in the event of a history of cancer chemotherapy , radiotherapy , or taking corticosteroids .

INTERACTIONS OF THE DRUG ACTONEL 30 MG WITH OTHER SUBSTANCES

Other drugs (especially digestive dressings or those containing calcium, magnesium or iron) should be taken away from this drug because they may reduce its intestinal absorption.

FERTILITY, PREGNANCY AND LACTATION

The effect of this medicine during pregnancy or lactation is not well known. As a precaution, its use is contraindicated in pregnant or breastfeeding women.

INSTRUCTIONS FOR USE AND DOSAGE OF THE DRUG ACTONEL 30 MG

This medication should be taken with a large glass of water (tap water or mineral water low in calcium and magnesium), in a sitting or standing position, without taking any drink (other than water) or drink. food (minimum 30 minutes before breakfast or at least 2 hours away from meals).

The tablets should be swallowed whole, without being chewed.

USUAL DOSE:

• Adult : 1 tablet per day, in cure of 2 months.

POSSIBLE SIDE EFFECTS OF ACTONEL 30 MG

Nausea, diarrhea , constipation , abdominal pain.

Bone and joint pain, muscle weakness, cramps.

Edema, weight loss, hypocalcemia .

Dizziness .

Bronchitis, sinusitis .

Skin rash .

Visual disturbances, corneal damage , dry eye, ringing in the ears, bedwetting .

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ACLASTA DRUG RANGE

 Drug family: Bisphosphonate

IN WHICH CASE IS THE DRUG ACLASTA PRESCRIBED?

This medicine belongs to the family of bisphosphonates (formerly diphosphonates). It works by blocking cells that destroy bone and fighting against demineralization; it therefore opposes the release of bone calcium into the blood. It reduces the risk of fracture due to osteoporosis .

It is used in the treatment of:

• osteoporosis , whether or not associated with prolonged treatment with corticosteroids , in postmenopausal women and men at high risk of fracture;

• Paget 's disease .

You can consult the following article(s):

• Osteoporosis

PRESENTATIONS OF THE DRUG ACLASTA

ACLASTA 5 mg  : solution for IV infusion  ; 100ml bottle

On prescription (List I) - Reimbursable at 65% -  Price:  €189.26 .

The prices mentioned do not take into account the pharmacist's " dispensing fees ".

COMPOSITION OF THE DRUG ACLASTA

	vial
Zoledronic acid	5mg

Active substances:Zoledronic acid,Zoledronic acid monohydrate

Excipients  : Water for injection, Mannitol , Sodium citrate

CONTRAINDICATIONS OF THE DRUG ACLASTA

This medicine should not be used in the following cases:

• allergy to drugs of the bisphosphonate family,

• hypocalcemia ,

• severe kidney failure ,

• pregnancy ,

• breastfeeding .

ATTENTION

Special monitoring is necessary in case of kidney malfunction, taking diuretics or drugs toxic to the kidneys and in the elderly. On the day of the infusion , it is recommended to drink at least half a liter of liquid before and after the treatment.

In the treatment of Paget 's disease , this medicine exposes you to a risk of hypocalcaemia which can result in neurological and muscular manifestations (tingling of the hands and feet, muscle cramps, convulsions ). A blood calcium test is recommended before the infusion and sufficient intakes of calcium and vitamin D are necessary for at least 10 days after the infusion .

Damage to the jaw bones (osteonecrosis) which may lead to tooth loss has been reported rarely in people taking bisphosphonates. A dental examination and preventive care may be necessary before starting treatment, especially in the event of a history of cancer chemotherapy , radiotherapy or the taking of corticosteroids . Good oral hygiene and regular dental monitoring are recommended to limit the risks. If you need dental care, tell your dentist about the administration of this medication. A patient card containing information on the risk of osteonecrosis should be given to you by your doctor or pharmacist.

In case of persistent pain, weakness or discomfort in the thigh, hip or groin, contact your doctor immediately; examinations must be carried out to look for a possible fracture of the femur.

Driver: this medication may cause dizziness or reduced alertness .

FERTILITY, PREGNANCY AND LACTATION

The effect of this drug during pregnancy and lactation is poorly known: its use is contraindicated in pregnant or breastfeeding women.

INSTRUCTIONS FOR USE AND DOSAGE OF THE DRUG ACLASTA

The solution must be administered by means of an infusion lasting at least 15 minutes and under no circumstances by direct intravenous injection.

USUAL DOSE:

• Adult over 18 :

  • Osteoporosis : 1 injection of 5 mg, once a year.

  • Paget 's disease : 1 single injection of 5 mg.

TIPS

Regular physical exercises adapted to age and physical condition help to limit the progression of osteoporosis .

Moderate alcohol consumption and smoking cessation are also recommended, as both alcohol and tobacco promote bone loss.

Flu - like illness (which may include fever, headache, fatigue, digestive disturbances , muscle or joint pain) frequently occurs within three days of drug infusion ; it can be fought by taking paracetamol or ibuprofen.

After opening the bottle, the solution should be used immediately. If this is not the case, it may possibly be stored at 2°C to 8°C for a maximum of 24 hours.

POSSIBLE SIDE EFFECTS OF THE DRUG ACLASTA

Very common (more than 10% of patients): fever.

Frequent (1 to 10% of patients): pain or redness at the injection site, nausea, vomiting, diarrhea , headache, dizziness , flu, cold, anemia , red eyes, heart rhythm disturbances , muscle or joint pain, bone pain.

Uncommon (less than 1 in 100 patients): difficult digestion, abdominal pain, constipation , dry mouth, heartburn, inflammation of the esophagus, skin rash , itching, sweating, insomnia or drowsiness, tingling, tremor, malaise, taste disturbances, dizziness , palpitations , high blood pressure, flushing of the face, cough, shortness of breath, cramps, neck or shoulder pain, joint swelling, increased creatinine .

Rare (less than 1 in 1,000 patients): uveitis , fracture of the femur, weakening of the jaw bones (see Warning) or the ear canal (which may result in pain, discharge or chronic ear infections) , impaired kidney function.

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RANGE OF MEDICINES ZOLEDRONIC ACID SANDOZ

 Drug family: Bisphosphonate

This drug is a generic of ACLASTA.

IN WHICH CASE IS ZOLEDRONIC ACID SANDOZ 5 MG PRESCRIBED?

This medicine belongs to the family of bisphosphonates (formerly diphosphonates). It works by blocking cells that destroy bone and fighting against demineralization; it therefore opposes the release of bone calcium into the blood. It reduces the risk of fracture due to osteoporosis .

It is used in the treatment of:

• osteoporosis , whether or not associated with prolonged treatment with corticosteroids , in postmenopausal women and men at high risk of fracture;

• Paget 's disease .

You can consult the following article(s):

• Osteoporosis

PRESENTATIONS OF THE DRUG ZOLEDRONIC ACID SANDOZ 5 MG

ZOLEDRONIC ACID SANDOZ 5 mg/100 ml  : solution for infusion  ; 100ml bottle

On prescription (List I) - Reimbursable at 65% -  Price:  €129.63 .

The prices mentioned do not take into account the pharmacist's " dispensing fees ".

COMPOSITION OF THE DRUG ZOLEDRONIC ACID SANDOZ 5 MG

	p flacon
Zoledronic acid	5 mg

Active substances:Zoledronic acid,Zoledronic acid monohydrate

Excipients : Eau ppi, Mannitol, Sodium citrate

CONTRAINDICATIONS OF THE DRUG ZOLEDRONIC ACID SANDOZ 5 MG

This medicine should not be used in the following cases:

• allergy to drugs of the bisphosphonate family,

• hypocalcemia ,

• severe kidney failure ,

• pregnancy ,

• breastfeeding .

ATTENTION

Special monitoring is necessary in case of kidney malfunction, taking diuretics or drugs toxic to the kidneys and in the elderly. On the day of the infusion , it is recommended to drink at least half a liter of liquid before and after the treatment.

In the treatment of Paget 's disease , this medicine exposes you to a risk of hypocalcaemia which can result in neurological and muscular manifestations (tingling of the hands and feet, muscle cramps, convulsions ). A blood calcium test is recommended before the infusion and sufficient intakes of calcium and vitamin D are necessary for at least 10 days after the infusion .

Damage to the jaw bones (osteonecrosis) which may lead to tooth loss has been reported rarely in people taking bisphosphonates. A dental examination and preventive care may be necessary before starting treatment, especially in the event of a history of cancer chemotherapy , radiotherapy or the taking of corticosteroids . Good oral hygiene and regular dental monitoring are recommended to limit the risks. If you need dental care, tell your dentist about the administration of this medication. A patient card containing information on the risk of osteonecrosis should be given to you by your doctor or pharmacist.

In case of persistent pain, weakness or discomfort in the thigh, hip or groin, contact your doctor immediately; examinations must be carried out to look for a possible fracture of the femur.

Driver: this medication may cause dizziness or reduced alertness .

FERTILITY, PREGNANCY AND LACTATION

The effect of this drug during pregnancy and lactation is poorly known: its use is contraindicated in pregnant or breastfeeding women.

INSTRUCTIONS FOR USE AND DOSAGE OF THE DRUG ZOLEDRONIC ACID SANDOZ 5 MG

The solution must be administered by means of an infusion lasting at least 15 minutes and under no circumstances by direct intravenous injection.

USUAL DOSE:

• Adult over 18 :

  • Osteoporosis : 1 injection of 5 mg, once a year.

  • Paget 's disease : 1 single injection of 5 mg.

TIPS

Regular physical exercises adapted to age and physical condition help to limit the progression of osteoporosis .

Moderate alcohol consumption and smoking cessation are also recommended, as both alcohol and tobacco promote bone loss.

Flu - like illness (which may include fever, headache, fatigue, digestive disturbances , muscle or joint pain) frequently occurs within three days of drug infusion ; it can be fought by taking paracetamol or ibuprofen.

After opening the bottle, the solution should be used immediately. If this is not the case, it may possibly be stored at 2°C to 8°C for a maximum of 24 hours.

POSSIBLE SIDE EFFECTS OF THE DRUG ZOLEDRONIC ACID SANDOZ 5 MG

Very common (more than 10% of patients): fever.

Frequent (1 to 10% of patients): pain or redness at the injection site, nausea, vomiting, diarrhea , headache, dizziness , flu, cold, anemia , red eyes, heart rhythm disturbances , muscle or joint pain, bone pain.

Uncommon (less than 1 in 100 patients): difficult digestion, abdominal pain, constipation , dry mouth, heartburn, inflammation of the esophagus, skin rash , itching, sweating, insomnia or drowsiness, tingling, tremor, malaise, taste disturbances, dizziness , palpitations , high blood pressure, flushing of the face, cough, shortness of breath, cramps, neck or shoulder pain, joint swelling, increased creatinine .

Rare (less than 1 in 1,000 patients): uveitis , fracture of the femur, weakening of the jaw bones (see Warning) or the ear canal (which may result in pain, discharge or chronic ear infections) , impaired kidney function.

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RANGE OF MEDICINES ZOLEDRONIC ACID MYLAN

 Drug family: Bisphosphonate

This drug is a generic of ACLASTA.

IN WHICH CASE IS ZOLEDRONIC ACID MYLAN 5 MG PRESCRIBED?

This medicine belongs to the family of bisphosphonates (formerly diphosphonates). It works by blocking cells that destroy bone and fighting against demineralization; it therefore opposes the release of bone calcium into the blood. It reduces the risk of fracture due to osteoporosis .

It is used in the treatment of:

• osteoporosis , whether or not associated with prolonged treatment with corticosteroids , in postmenopausal women and men at high risk of fracture;

• Paget 's disease .

You can consult the following article(s):

• Osteoporosis

PRESENTATIONS OF THE DRUG ZOLEDRONIC ACID MYLAN 5 MG

ZOLEDRONIC ACID MYLAN 5 mg/100 ml  : solution for infusion  ; 100ml bottle

On prescription (List I) - Reimbursable at 65% -  Price:  €129.63 .

The prices mentioned do not take into account the pharmacist's " dispensing fees ".

COMPOSITION OF THE DRUG ZOLEDRONIC ACID MYLAN 5 MG

	vial
Zoledronic acid	5mg

Active substances:Zoledronic acid,Zoledronic acid monohydrate

Excipients  : Water for injection, Mannitol , Sodium citrate

CONTRAINDICATIONS OF THE DRUG ZOLEDRONIC ACID MYLAN 5 MG

This medicine should not be used in the following cases:

• allergy to drugs of the bisphosphonate family,

• hypocalcemia ,

• severe kidney failure ,

• pregnancy ,

• breastfeeding .

ATTENTION

Special monitoring is necessary in case of kidney malfunction, taking diuretics or drugs toxic to the kidneys and in the elderly. On the day of the infusion , it is recommended to drink at least half a liter of liquid before and after the treatment.

In the treatment of Paget 's disease , this medicine exposes you to a risk of hypocalcaemia which can result in neurological and muscular manifestations (tingling of the hands and feet, muscle cramps, convulsions ). A blood calcium test is recommended before the infusion and sufficient intakes of calcium and vitamin D are necessary for at least 10 days after the infusion .

Damage to the jaw bones (osteonecrosis) which may lead to tooth loss has been reported rarely in people taking bisphosphonates. A dental examination and preventive care may be necessary before starting treatment, especially in the event of a history of cancer chemotherapy , radiotherapy or the taking of corticosteroids . Good oral hygiene and regular dental monitoring are recommended to limit the risks. If you need dental care, tell your dentist about the administration of this medication. A patient card containing information on the risk of osteonecrosis should be given to you by your doctor or pharmacist.

In case of persistent pain, weakness or discomfort in the thigh, hip or groin, contact your doctor immediately; examinations must be carried out to look for a possible fracture of the femur.

Driver: this medication may cause dizziness or reduced alertness .

FERTILITY, PREGNANCY AND LACTATION

The effect of this drug during pregnancy and lactation is poorly known: its use is contraindicated in pregnant or breastfeeding women.

INSTRUCTIONS FOR USE AND DOSAGE OF THE DRUG ZOLEDRONIC ACID MYLAN 5 MG

The solution must be administered by means of an infusion lasting at least 15 minutes and under no circumstances by direct intravenous injection.

USUAL DOSE:

• Adult over 18 :

  • Osteoporosis : 1 injection of 5 mg, once a year.

  • Paget 's disease : 1 single injection of 5 mg.

TIPS

Regular physical exercises adapted to age and physical condition help to limit the progression of osteoporosis .

Moderate alcohol consumption and smoking cessation are also recommended, as both alcohol and tobacco promote bone loss.

Flu - like illness (which may include fever, headache, fatigue, digestive disturbances , muscle or joint pain) frequently occurs within three days of drug infusion ; it can be fought by taking paracetamol or ibuprofen.

After opening the bottle, the solution should be used immediately. If this is not the case, it may possibly be stored at 2°C to 8°C for a maximum of 24 hours.

POSSIBLE SIDE EFFECTS OF THE DRUG ZOLEDRONIC ACID MYLAN 5 MG

Very common (more than 10% of patients): fever.

Frequent (1 to 10% of patients): pain or redness at the injection site, nausea, vomiting, diarrhea , headache, dizziness , flu, cold, anemia , red eyes, heart rhythm disturbances , muscle or joint pain, bone pain.

Uncommon (less than 1 in 100 patients): difficult digestion, abdominal pain, constipation , dry mouth, heartburn, inflammation of the esophagus, skin rash , itching, sweating, insomnia or drowsiness, tingling, tremor, malaise, taste disturbances, dizziness , palpitations , high blood pressure, flushing of the face, cough, shortness of breath, cramps, neck or shoulder pain, joint swelling, increased creatinine .

Rare (less than 1 in 1,000 patients): uveitis , fracture of the femur, weakening of the jaw bones (see Warning) or the ear canal (which may result in pain, discharge or chronic ear infections) , impaired kidney function.

Read More