Mixed micelles:
Mixed micelles contain fatty acids decomposed by surface-active agents or bile salts. The effect of mixed micelles on the absorption of the drug has been demonstrated by Muranishi. Mixed solvents are effective absorbents for compounds such as heparin, streptomycin, gentamycin, and insulin. The effect of mixed micelles on the absorption of the drug tends to be greater in the ventral region of the gastrointestinal tract. The absorption increase mechanism is unknown. Some reports claim they are safe to use while other reports have reported a disturbing effect in epithelial intestinal cells.
Mixed micelles contain fatty acids decomposed by surface-active agents or bile salts. The effect of mixed micelles on the absorption of the drug has been demonstrated by Muranishi. Mixed solvents are effective absorbents for compounds such as heparin, streptomycin, gentamycin, and insulin. The effect of mixed micelles on the absorption of the drug tends to be greater in the ventral region of the gastrointestinal tract. The absorption increase mechanism is unknown. Some reports claim they are safe to use while other reports have reported a disturbing effect in epithelial intestinal cells.