Cyclosporine is a strong immunosuppressant that is almost free from toxic effects of purity, but is remarkably toxic to the kidney. It is especially useful to prevent the rejection of taste and to prevent bait disease against the host. The dose is adjusted according to plasma cyclosporine concentrations and kidney function. The increase in plasma creatinine and urinary serum urinain in the blood during the first few weeks may require dose reduction. Corticosteroids such as prednisolone (section 3.8) have a large immunosuppressive activity and can also be used to prevent rejection of organ stings.
