Mcq fibrous dysplasia associated with:
a- rickets and gout osteomalacia***
b- rheumatoid artheritis
c- monostatic type with takyasso syndrome
d- monostatic type with McCune-Albright syndrome
d- cardiomegally
N.B → Although fibrous dysplasia is usually sporadic, a number of associations are well recognised:
McCune-Albright syndrome - in 2-3 % of cases with the polyostotic form isolated endocrinopathy without the full McCune-Albright syndrome precocious puberty in girls
hyperthyroidism
hyperparathyroidism : renal stones, calcinosis
acromegaly
diabetes mellitus
Cushing syndrome : osteoporosis, acne
growth retardation
Mazabraud syndrome - soft-tissue myxomas (rare) ; typically multiple intramuscular lesions in vicinity of most severely affected bone
Hypophosphatemic rickets/osteomalacia is recognized as a rare complication of FD/MAS so the correct answer is rickets ????
Hyperthyroidism, acromeea/v, Cnshing's syndrome:, gvnaecrnnastia
and parathvroid enlargement have all been reported in association
with polyostotic fibrous dysplasia. (Sutton)
a- rickets and gout osteomalacia***
b- rheumatoid artheritis
c- monostatic type with takyasso syndrome
d- monostatic type with McCune-Albright syndrome
d- cardiomegally
N.B → Although fibrous dysplasia is usually sporadic, a number of associations are well recognised:
McCune-Albright syndrome - in 2-3 % of cases with the polyostotic form isolated endocrinopathy without the full McCune-Albright syndrome precocious puberty in girls
hyperthyroidism
hyperparathyroidism : renal stones, calcinosis
acromegaly
diabetes mellitus
Cushing syndrome : osteoporosis, acne
growth retardation
Mazabraud syndrome - soft-tissue myxomas (rare) ; typically multiple intramuscular lesions in vicinity of most severely affected bone
Hypophosphatemic rickets/osteomalacia is recognized as a rare complication of FD/MAS so the correct answer is rickets ????
Hyperthyroidism, acromeea/v, Cnshing's syndrome:, gvnaecrnnastia
and parathvroid enlargement have all been reported in association
with polyostotic fibrous dysplasia. (Sutton)