ACTIVELLE DRUG RANGE
Drug family: Estroprogestogen
IN WHICH CASE IS THE DRUG ACTIVELLE PRESCRIBED?
This medication contains estradiol, intended to correct an estrogen deficiency , and norethisterone, a progestogen which has a protective effect on the uterus.
It is used to treat certain symptoms of menopause (hot flushes, vaginal dryness, etc.) and to prevent osteoporosis in postmenopausal women.
You can consult the following article(s):
- Menopause
- Osteoporosis
PRESENTATIONS OF THE DRUG ACTIVELLE
The prices mentioned do not take into account the pharmacist's " dispensing fees ".
CONTRAINDICATIONS OF THE DRUG ACTIVELLE
thromboembolic accident ( phlebitis , pulmonary embolism, etc.) occurring during treatment;
hormone-dependent cancer ;
intermittent genital bleeding (the origin of this bleeding must be determined by examinations before starting treatment);
severe liver disease;
pregnancy ;
breastfeeding .
ATTENTION
Studies have shown an increased risk of developing breast cancer in women who received prolonged treatment for menopausal symptoms . Treatment should therefore be prescribed at the lowest effective dose and for the shortest possible duration. In the absence of disorders, its prescription should not be systematic.
An initial assessment followed by regular medical supervision is necessary, especially in the following cases: arterial hypertension , diabetes , benign tumor of the liver or uterus, endometriosis , cholelithiasis , migraines , epilepsy , asthma , otosclerosis , renal insufficiency or cardiac, hypertriglyceridaemia , systemic lupus erythematosus , obesity , family history of breast cancer or thromboembolic accident.
Stop taking this medication and consult your doctor if any of the following symptoms appear : severe and unusual headaches, jaundice, significant rise in blood pressure , painful swelling of a leg, shortness of breath brutal.
If you have to undergo surgery or remain bedridden, tell your doctor; it may be necessary to temporarily stop treatment.
INTERACTIONS OF THE DRUG ACTIVELLE WITH OTHER SUBSTANCES
The effectiveness of the treatment may be reduced by taking an enzyme-inducing drug at the same time .
FERTILITY, PREGNANCY AND LACTATION
Given the indications, this drug is not used in pregnant or breastfeeding women.
INSTRUCTIONS FOR USE AND DOSAGE OF THE DRUG ACTIVELLE
Take 1 tablet per day, preferably at the same time, without interruption between 2 packs.
TIPS
Irregular genital bleeding may also occur during the first 2 or 3 months of treatment; if this bleeding persists longer, consult your doctor.
POSSIBLE SIDE EFFECTS OF THE DRUG ACTIVELLE
Headaches, breast tension, vaginal candidiasis , fatigue, insomnia, depression , increased blood pressure , abdominal pain, bloating , nausea, itching, edema, weight gain.
Intermittent genital bleeding (report to your doctor).
Clinical trials involving long-term treatment combining an estrogen and a progestogen have shown increased risks of benign or malignant tumor of the breast or uterus, thromboembolic accident, gallbladder stones, spots dark on the face.
How many mg of estrogen should I take for HRT?
Adults—2.5 to 7.5 mg a day. This dose may be divided up and taken in smaller doses. Your doctor may want you to take the medicine each day or only on certain days of the month.
What is normal estradiol level on HRT?
Results are given in picograms per milliliter (pg/mL). Normal levels for estradiol are: 30 to 400 pg/mL for premenopausal women. 0 to 30 pg/mL for postmenopausal women.
What is the normal range for estradiol levels on HRT?
Doses and routes of administration
Indeed, blood levels of estradiol associated with the standard dose of HRT (1 mg of oral estradiol or 50 mcg estradiol patch) are between 150-370 pmol/L. It is therefore accepted that blood levels greater than 700 pmol/L should be avoided.
How many days should you cycle in HRT?
There are 2 types of cyclical HRT: monthly HRT – you take oestrogen every day, and take progestogen alongside it for the last 14 days of your menstrual cycle. 3-monthly HRT – you take oestrogen every day, and take progestogen alongside it for around 14 days every 3 months.
Is Activella a hormone?
Activella is a prescription medicine that contains two kinds of hormones, an estrogen and a progestin. Activella is used after menopause to: Estrogens are hormones made by a woman's ovaries. The ovaries normally stop making estrogens when a woman is between 45 and 55 yrs old.
How long do you stay on HRT tablets?
Most women are able to stop taking HRT after their menopausal symptoms finish, which is usually two to five years after they start (but in some cases this can be longer). Gradually decreasing your HRT dose is usually recommended, rather than stopping suddenly.
What is estradiol 0.5 mg used for?
Estradiol is used to treat menopause symptoms such as hot flashes and vaginal changes, and to prevent osteoporosis (bone loss) in menopausal women.
Does Activella help with anxiety?
Well worth the relief!" For Postmenopausal Symptoms "I have been taking Activella for 4 months now. It immediately alleviated hot flashing and anxiety/nervousness/irritability. However, I think it is beginning to cause headaches.
How much estradiol is too much?
What's considered "high"? In terms of the Modern Fertility Hormone Test, levels of estradiol (an estrogen) in premenopausal people with ovaries on day 3 of their cycle are "high" if they're above 115 pg/mL. Symptoms of high estrogen levels include: Heavier periods or increased frequency of periods.
Is Activelle a hormone replacement?
Activelle and associated names, estradiol 0.5mg and norethisterone acetate 0.1 mg film-coated tablets is a continuous combined hormone replacement therapy (HRT) for oestrogen deficiency symptoms in women more than one year after menopause.
Is Activelle good for menopause?
It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. The progestin in this medication helps to reduce the risk of cancer of the uterus which can be caused by using estrogen.
What is Activella prescribed for?
Activella (estradiol / norethindrone) is a combination medication containing estradiol and norethindrone that works well to treat symptoms of low estrogen levels, such as hot flashes, night sweats, and vaginal dryness, related to menopause.
What is the schedule for Activelle?
One tablet should be taken orally once a day without interruption, preferably at the same time every day. For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration (see Precautions) should be used.
How much estrogen is in Activella?
Each tablet of Activella 0.5 mg/ 0.1 mg contains 0.5 mg of estradiol and 0.1 mg of norethindrone acetate.
