Fanconi's anemia:
The syndrome is inherited as an autosomal recessive. Infected children are usually young and underweight at birth. Death may usually occur within several years and the first sign of serious complications is bone marrow failure.
Clinical manifestations:
Skin manifestations:
- The appearance of blood bruising is easily introduced and packer usually appears at age 4 10 years.
- Hyperpigmentation and structural abnormalities are also characteristic features.
- Freckles brown macular (Freckles) freckles and occurs mainly on areas exposed to the sun, abdomen, genital areas and emotional surfaces appear to be affected mainly.
- Diaphragm deficiency is often found in affected areas.
General features:
- Increased bone marrow deficiency during childhood and adolescence.
- Thrombocytopenia, anemia, leukopenia and osteoporosis are unproductive.
- The main structural distortions are the absence or lack of manufacturing at least one of the two thumbs.
- Absence or lack of the manufacture of radiance is also common.
- Kidney abnormalities are also frequently found.
- Intelligence is not usually affected.
- There is a high rate of leukemia and other blisters in these children.
- There is a high rate of diabetes and eczema.
Treatment:
Bone marrow function can be induced with corticosteroids and androgenic esters.
And oxythemalone.
Bone marrow transplantation has been successfully used to treat patients, but caution should be exercised to avoid the use of alkylating agents in pre-implantation.
The syndrome is inherited as an autosomal recessive. Infected children are usually young and underweight at birth. Death may usually occur within several years and the first sign of serious complications is bone marrow failure.
Clinical manifestations:
Skin manifestations:
- The appearance of blood bruising is easily introduced and packer usually appears at age 4 10 years.
- Hyperpigmentation and structural abnormalities are also characteristic features.
- Freckles brown macular (Freckles) freckles and occurs mainly on areas exposed to the sun, abdomen, genital areas and emotional surfaces appear to be affected mainly.
- Diaphragm deficiency is often found in affected areas.
General features:
- Increased bone marrow deficiency during childhood and adolescence.
- Thrombocytopenia, anemia, leukopenia and osteoporosis are unproductive.
- The main structural distortions are the absence or lack of manufacturing at least one of the two thumbs.
- Absence or lack of the manufacture of radiance is also common.
- Kidney abnormalities are also frequently found.
- Intelligence is not usually affected.
- There is a high rate of leukemia and other blisters in these children.
- There is a high rate of diabetes and eczema.
Treatment:
Bone marrow function can be induced with corticosteroids and androgenic esters.
And oxythemalone.
Bone marrow transplantation has been successfully used to treat patients, but caution should be exercised to avoid the use of alkylating agents in pre-implantation.
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skin diseases