Neutrophil disorders:
This syndrome may be congenital or acquired.
- Chronic neutropenia: chronic chronic neutropenia in childhood leads to a high mortality rate and is inherited as an autosomal recessive or autosomal dominant.
- Lack of neutrophils acquired: may result from drugs and osteoporosis and also occur transiently in the context of fevers (fever).
General features:
Usually begins during the first months of life as neutrophils appear to be primarily responsible for protecting these surfaces of the body that are in direct contact with the external environment.
Frequent skin infections:
When the number of neutrophils is less than 500 mm, the patient is at significant risk of infection.
Skin abscesses, boils, cellulitis are the most common forms of infection such as otitis media, mouth inflammation and gingivitis are common and are commonly occurring due to gonadal staphylocytosis and are less common Gram negative negatives such as E. coli and diphtheria strains (Ciudomonas).
Systemic infections:
Other common infections include lung abscesses, pneumonia, meningitis and sepsis, which are serious complications.
- Fungal infections are a particular problem caused by aspergillus (Asperpilus) and Candida.
- The eczema around the mouth: often diagnosed with zinc deficiency rash.
Treatment:
Bone marrow transplant.
Congenital neutropenia:
It is an autosomal dominant disorder in which the neutrophils pass away at regular intervals during about 21 days.
Clinical manifestations:
The first manifestations of childhood are:
- Frequent heat rise.
- Oral ulceration.
- Lymph node necrosis of cervical.
- Dermal dermatosis.
Treatment:
The condition tends to improve spontaneously after several years. Treatment with human caterpillars and the colony stimulating factor appears to be encouraging in the treatment.
This syndrome may be congenital or acquired.
- Chronic neutropenia: chronic chronic neutropenia in childhood leads to a high mortality rate and is inherited as an autosomal recessive or autosomal dominant.
- Lack of neutrophils acquired: may result from drugs and osteoporosis and also occur transiently in the context of fevers (fever).
General features:
Usually begins during the first months of life as neutrophils appear to be primarily responsible for protecting these surfaces of the body that are in direct contact with the external environment.
Frequent skin infections:
When the number of neutrophils is less than 500 mm, the patient is at significant risk of infection.
Skin abscesses, boils, cellulitis are the most common forms of infection such as otitis media, mouth inflammation and gingivitis are common and are commonly occurring due to gonadal staphylocytosis and are less common Gram negative negatives such as E. coli and diphtheria strains (Ciudomonas).
Systemic infections:
Other common infections include lung abscesses, pneumonia, meningitis and sepsis, which are serious complications.
- Fungal infections are a particular problem caused by aspergillus (Asperpilus) and Candida.
- The eczema around the mouth: often diagnosed with zinc deficiency rash.
Treatment:
Bone marrow transplant.
Congenital neutropenia:
It is an autosomal dominant disorder in which the neutrophils pass away at regular intervals during about 21 days.
Clinical manifestations:
The first manifestations of childhood are:
- Frequent heat rise.
- Oral ulceration.
- Lymph node necrosis of cervical.
- Dermal dermatosis.
Treatment:
The condition tends to improve spontaneously after several years. Treatment with human caterpillars and the colony stimulating factor appears to be encouraging in the treatment.
Labels
skin diseases