About 7% of the lipid hormone is metabolized to dihydrotestosterone DHT by 5-α reductase in many organs, such as the liver, seminal vesicles and prostate gland (Randall, 1994). About 0.3% of the hormone metabolizes to estradiol Estradiol (E2) is mediated by the enzyme Aromatase as in the brain, liver and fatty tissues (Meinhardt & Mullis, 2002).
