Drug injection by dermis.. Suboptimal treatment of scopolamine. Clonidine, estradiol, nicotine, nitroglycerin and scopolamine



Since the introduction of subcutaneous treatment of scopolamine, many dendritic delivery systems have been developed for systemic effectiveness. The most important advantages of the delivery route include the continuous release of the drug within a specified time and a few pre-systemic clearance, the possibility of easily withdrawing the medicine by simple removal of the drug delivery device, and is convenient for the patient.
Some of the disadvantages of this route are due to the skin-related properties of the skin and skin interactions and the relatively large size of the dose.
Dermal delivery is an effective option only in drugs that are generally given in small doses (<10 and="" approved="" clonidine="" commonly="" drugs="" estradiol="" good="" have="" include="" membrane="" mg="" nicotine="" nitroglycerin="" p="" penetration="" properties.="" scopolamine.="" which="">