Anticholinergic antidepressants contrast the effects of non-depolarizing muscle relaxants such as pancuronium, but prolong the effect of competitive depolarizing muscle relaxants such as suxamethonium.
Neostigmine is the specific drug to counteract the competitive blockade, showing its effect within a minute of intravenous injection, and lasts for 20-30 minutes.
The macroscopic effects of neurostigmine can be prevented by slow heart and excessive salivation by giving atropine with or before the neostigmine.
Neostigmine is the specific drug to counteract the competitive blockade, showing its effect within a minute of intravenous injection, and lasts for 20-30 minutes.
The macroscopic effects of neurostigmine can be prevented by slow heart and excessive salivation by giving atropine with or before the neostigmine.