The fate of the toxic substance that enters the body varies from person to person. This is due to many internal and external factors that interfere with the absorption, distribution, conversion and discharge of the poison.
Genetic factors: The effect of toxic substances on some people is due to a genetic defect in the enzymes required for the metabolism of this toxic substance, for example, people with a deficiency of enzyme (glucose-6-phosphate dehydrogenase) prone to cracking in Blood cells when exposed to aspirin.
2. Age: It has been shown that the effectiveness of most of the enzymes needed for the metabolism of toxins, especially conjugation is weaker in infants and elderly than in adults, so they are more affected by the name.
3. Pregnancy: During pregnancy and during the use of contraceptives, the effectiveness of enzymes that contribute to the metabolism of toxins, especially the cytochrome, decreases and the ability to mate in late pregnancy is reduced. These disorders increase the susceptibility of pregnant women to toxic substances.
4 - The nutritional status of the toxin: If the stomach is free from food, it increases the absorption of poison and the emergence of symptoms. The type of food in the stomach affects the speed of absorption, fatty food delays emptying and thus delay the arrival of poison to the intestine and absorb it.
5 - The health status of the toxin: Lack of liver failure ability to metabolize toxins and increase the impact on the bad body and the same applies to the lack of kidney, which reduces the emptying of toxins and increase the effects of toxic and in contrast some diseases make the patient more tolerant of some toxins from healthy, This is the case with people with anaphylaxis who carry hypnotics and sedatives in much larger amounts than the healthy ones.
6 - Tolerance: The treatment of toxins in a few increments and gradual increase, at intervals are somewhat different leads to the return of the person, that is, the body becomes resistant to the impact of this toxic if taken in amounts harmful to other people. The habit is easy for organic toxins such as morphine, cocaine and alcohol. Those who are addicted to these toxins have a large amount of lethal to ordinary people.
Genetic factors: The effect of toxic substances on some people is due to a genetic defect in the enzymes required for the metabolism of this toxic substance, for example, people with a deficiency of enzyme (glucose-6-phosphate dehydrogenase) prone to cracking in Blood cells when exposed to aspirin.
2. Age: It has been shown that the effectiveness of most of the enzymes needed for the metabolism of toxins, especially conjugation is weaker in infants and elderly than in adults, so they are more affected by the name.
3. Pregnancy: During pregnancy and during the use of contraceptives, the effectiveness of enzymes that contribute to the metabolism of toxins, especially the cytochrome, decreases and the ability to mate in late pregnancy is reduced. These disorders increase the susceptibility of pregnant women to toxic substances.
4 - The nutritional status of the toxin: If the stomach is free from food, it increases the absorption of poison and the emergence of symptoms. The type of food in the stomach affects the speed of absorption, fatty food delays emptying and thus delay the arrival of poison to the intestine and absorb it.
5 - The health status of the toxin: Lack of liver failure ability to metabolize toxins and increase the impact on the bad body and the same applies to the lack of kidney, which reduces the emptying of toxins and increase the effects of toxic and in contrast some diseases make the patient more tolerant of some toxins from healthy, This is the case with people with anaphylaxis who carry hypnotics and sedatives in much larger amounts than the healthy ones.
6 - Tolerance: The treatment of toxins in a few increments and gradual increase, at intervals are somewhat different leads to the return of the person, that is, the body becomes resistant to the impact of this toxic if taken in amounts harmful to other people. The habit is easy for organic toxins such as morphine, cocaine and alcohol. Those who are addicted to these toxins have a large amount of lethal to ordinary people.
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Poison