Which of the following side effects is associated with the use of norepinephrine.. Ischemic damage due to vasoconstriction and tissue hypoxia

Which of the following side effects is associated with the use of norepinephrine:
A. Nausea and vomiting.
B. Ischemic damage due to vasoconstriction and tissue hypoxia.***
C. Hypoglycemia due to increase insulin reiease.
D. Skin rashes.
E. Headache and constipation.