Giving insulin in the form of tablets for oral
There is no doubt that giving oral medication is the appropriate way and comfortable for patients.
And has been the experience of giving insulin in the form of tablets and oral solutions but that method is not effective because of the cracking of the hormone insulin and lack of effectiveness by digestive enzymes in the stomach.
And there are promising experiments are made by a team of Chinese scientists in January 2007 on experimental animals, specifically rats updated sugar and giving insulin in the form of oral solution. The main method encapsulates the hormone insulin substance known as Kitusan Chitosan , A chemical extracted from seashell shrimp,
The crabs are made in the form of very small particles. And then put those small molecules in aqueous solution given by mouth in experimental animals. The results of the study showed that giving insulin in this way led to the intestinal absorption of insulin and bringing them to the blood well and led to a reduction in the level of sugar in the blood. Work is currently underway to see if insulin was given in this way in humans will lead to similar results are good.
Can insulin be taken in pill form?
The result is better glucose control, reduced hyper and hypoglycemia, and less weight gain. In addition, oral insulin is easier for diabetics to incorporate into their daily routine because they simply take a pill, removing the need for multiple daily injections and continual glucose measurements.
Why insulin Cannot be taken orally as a tablet and must be injected?
Insulin is a peptide hormone, therefore, destroyed by gastric acid if taken orally. Intradermal absorption of insulin is not reliable, and it cannot mimic physiological insulin secretion. In addition, intradermal, intramuscular and intravenous therapy is not suitable for self-administration daily.
What happens if you ingest insulin orally?
Despite poor bioavailability (1%) when taken orally, insulin may produce symptomatic hypoglycemia with a massive ingestion. Vigilant blood glucose monitoring, supportive care with glucose replacement therapy, and admission to the hospital for observation may be required.
Why can't insulin be administered as a tablet or capsule?
You take insulin as a shot. You can't take it like a pill because normal digestion would destroy it. There are several different types, and they all work in different ways.