Down syndrome (Mongolian):
Is the most common chromosomal anomalies, characterized by black spots, bluish in different sizes and multiple forms occurring in the neonatal region of the newborn, often in the Orientals. Mongolian stains usually disappear during childhood.
Down syndrome accounts for about a third of severe and moderate mental retardation in school-age children.
Causation:
Most cases result from triglyceride 21, in which the excess chromosome, which is abnormally derived during the split, is usually originated from the mother.
The infected child has a normal number (46) of the chromosomes but one of the natural parents clinically carries the exchange of the part of the chromosome 21.
Clinical manifestations:
General features:
The facial appearance is personalized and characterized by:
- Small head, flat face, and small ears.
- Short nose.
- Two eyes resembling Mongolians with small cleft lip and folds above the dead.
- thick eyelids with short, scattered and divergent eyebrows.
- Irritant deficiency with irradiated spots (Burchfield patches).
- Short limbs and joints with loose ligaments.
- The fingers are short and conical and sometimes linked to a membrane (dried).
- The small finger is often curved.
Skin manifestations:
- At birth, the skin is normal.
- In early childhood there is softness in the skin.
- Between the ages of 5 and 10 years the skin becomes very dry and less flexible.
- Generalized dryness at the age of 15 years.
- The surface of the skin is dry with a dry skin.
- Chronic gouty eruption on the areas above the sheath and the shoulders.
- Common skin manifestations such as chronic inflammation of the eyelid inflammation of the nasal nasal gonorrhea.
Ringworm:
- The cheeks are often reddish.
- The peripheral circulation is weak, blue endings may occur and the gray (lead) nets are visible throughout the year on the thighs, buttocks and torso.
- The lines of the soles of the hand: include a single line in the fifth finger and increase the rate of urticaria in the fingers.
The manifestations of mucous membranes:
- Cracking and thickening of the lips.
- The tongue sips in all cases.
- Diseases such as: "Elastosis Perforoms and Syringomata" occur more often than natural persons.
Hair manifestations:
- Hair may be natural, but often it is soft and may be deficient pigment.
- alopecia alveolar.
Dental manifestations:
- The teeth are incomplete and finally may fall.
Other aspects:
- The limbs are small, the joints are loose, the fingers are short and conical, and sometimes they are attached to a membrane.
Mental retardation is a serious complication.
IQ IQ is usually less than 50.
Cardiac abnormalities.
Epilepsy.
Hypothyroidism.
Blood leukemia.
Frequent respiratory infections.
When serious deformities occur, death usually occurs during childhood.
Is the most common chromosomal anomalies, characterized by black spots, bluish in different sizes and multiple forms occurring in the neonatal region of the newborn, often in the Orientals. Mongolian stains usually disappear during childhood.
Down syndrome accounts for about a third of severe and moderate mental retardation in school-age children.
Causation:
Most cases result from triglyceride 21, in which the excess chromosome, which is abnormally derived during the split, is usually originated from the mother.
The infected child has a normal number (46) of the chromosomes but one of the natural parents clinically carries the exchange of the part of the chromosome 21.
Clinical manifestations:
General features:
The facial appearance is personalized and characterized by:
- Small head, flat face, and small ears.
- Short nose.
- Two eyes resembling Mongolians with small cleft lip and folds above the dead.
- thick eyelids with short, scattered and divergent eyebrows.
- Irritant deficiency with irradiated spots (Burchfield patches).
- Short limbs and joints with loose ligaments.
- The fingers are short and conical and sometimes linked to a membrane (dried).
- The small finger is often curved.
Skin manifestations:
- At birth, the skin is normal.
- In early childhood there is softness in the skin.
- Between the ages of 5 and 10 years the skin becomes very dry and less flexible.
- Generalized dryness at the age of 15 years.
- The surface of the skin is dry with a dry skin.
- Chronic gouty eruption on the areas above the sheath and the shoulders.
- Common skin manifestations such as chronic inflammation of the eyelid inflammation of the nasal nasal gonorrhea.
Ringworm:
- The cheeks are often reddish.
- The peripheral circulation is weak, blue endings may occur and the gray (lead) nets are visible throughout the year on the thighs, buttocks and torso.
- The lines of the soles of the hand: include a single line in the fifth finger and increase the rate of urticaria in the fingers.
The manifestations of mucous membranes:
- Cracking and thickening of the lips.
- The tongue sips in all cases.
- Diseases such as: "Elastosis Perforoms and Syringomata" occur more often than natural persons.
Hair manifestations:
- Hair may be natural, but often it is soft and may be deficient pigment.
- alopecia alveolar.
Dental manifestations:
- The teeth are incomplete and finally may fall.
Other aspects:
- The limbs are small, the joints are loose, the fingers are short and conical, and sometimes they are attached to a membrane.
Mental retardation is a serious complication.
IQ IQ is usually less than 50.
Cardiac abnormalities.
Epilepsy.
Hypothyroidism.
Blood leukemia.
Frequent respiratory infections.
When serious deformities occur, death usually occurs during childhood.