Particle size:
Particle size plays a large role in drug absorption. The solubility rate of the solid particles is proportional to the surface area and thus with fineness of the particles. The reduction of particle size is used to increase the absorption of a large number of low-calming drugs such as bishydroxycoumarin, digoxin, griseofulvin, nitrofurantoin and tolubutamide.
Griseofulvin is very low solubility with water and the size of the physical particles leads to poor and irregular absorption. The size of micronutrients increases the absorption, but this improvement is greater when they are characterized by particles with ultramericrosize as a monomolecular glycol.
Particle size plays a large role in drug absorption. The solubility rate of the solid particles is proportional to the surface area and thus with fineness of the particles. The reduction of particle size is used to increase the absorption of a large number of low-calming drugs such as bishydroxycoumarin, digoxin, griseofulvin, nitrofurantoin and tolubutamide.
Griseofulvin is very low solubility with water and the size of the physical particles leads to poor and irregular absorption. The size of micronutrients increases the absorption, but this improvement is greater when they are characterized by particles with ultramericrosize as a monomolecular glycol.