Correlation of dosage levels, absorption efficiency, total bioavailability, distribution, filtration and susceptibility to lipid breakdown



Tracking the levels of the circulating drug achieved for the dose, absorption efficiency, total bioavailability, distribution and clearance. The largest determinant of the size of the drug distribution is its ability to dissolve fat. The higher the lipid solubility, the greater the drug's ability to cross the biofilms and move to the extravascular environment, especially to the liposuction and central nervous system (CNS).
Many drugs are associated with plasma proteins, especially plasma albumin. However, although plasma drug binding is dynamic and inverse, any drug associated with a specific time is bound to the size of the plasma and thus can not participate in extracellular distribution.