Chemical agents for the absorption of drugs:
Many chemical options can be used to improve stability and systemic availability. For example, esters can be prepared from both acids and bases for the production of more stable derivatives that adapt to the active compound once absorbed. The acids and bases tend to increase their stability and decay when present in salts. Application of dissolved penicillin salts increases circulatory antibody levels more than in acidic free state. When the weak acid salt is dissolved in the stomach, this will generate a relatively high spreading layer, which in turn increases solubility. For the same reason theoretically used for essential drugs. However, the effect of phagocytes at this stage will be overwhelmed by the presence of very low pH in stomach fluids. As a result, essential drug salts are used mainly for handling, solubility and solubility.
Many chemical options can be used to improve stability and systemic availability. For example, esters can be prepared from both acids and bases for the production of more stable derivatives that adapt to the active compound once absorbed. The acids and bases tend to increase their stability and decay when present in salts. Application of dissolved penicillin salts increases circulatory antibody levels more than in acidic free state. When the weak acid salt is dissolved in the stomach, this will generate a relatively high spreading layer, which in turn increases solubility. For the same reason theoretically used for essential drugs. However, the effect of phagocytes at this stage will be overwhelmed by the presence of very low pH in stomach fluids. As a result, essential drug salts are used mainly for handling, solubility and solubility.