Which is not associated with abetalipoproteinemia:
a. Acanthocytes in the peripheral blood.
b. Hereditary spherocytosis.
c. Malabsorption and fatty stools
(b) Hereditary spherocytosis is due to spectrin deficiency.
Abetalipoproteinemia is a lipoprotein abnormality of absent LDL due to autosomal recessive abnormality in the synthesis of apoB + failure of chylomicron formation leading to malabsorption of fats + fat soluble vitamins + adrenal dysfunction. 50-70% of RBCs have spinal projections (acanthocytes).
a. Acanthocytes in the peripheral blood.
b. Hereditary spherocytosis.
c. Malabsorption and fatty stools
(b) Hereditary spherocytosis is due to spectrin deficiency.
Abetalipoproteinemia is a lipoprotein abnormality of absent LDL due to autosomal recessive abnormality in the synthesis of apoB + failure of chylomicron formation leading to malabsorption of fats + fat soluble vitamins + adrenal dysfunction. 50-70% of RBCs have spinal projections (acanthocytes).