Regarding concentration of urine.. Proximal tubules return 75% of filtered water

Regarding concentration of urine;
a. Proximal tubules return 75% of filtered water.
b. Distal convoluted tubules deliver 40-60L of fluid to collecting tubules / day.
c. Osmotic pressure in renal cortex is higher than in medulla.
d. ADH acts on all parts of nephrone.
e. Aldosterone increase Na excretion.

a. Approximately 80% of the water and NaCl contenet together with glucose, phosphate, and amino acids are reabsorbed in the proximal tubule. About 20% of the tubular fluid enters the loop of Henle where water is passively aborbed; 6ml per minute of concentrated tubular fluid now enters the distal tubule, where there is an active reabsorption of sodium. The fluid leaves the distal tubule at a rate of approximately 1ml per minute passing into the collecting ducts in the form of urine. Aldosteron is relased due to ineffective arterial pressure in the kidney. It causes sodium reabsorption which raises plasma osmolality. ADH increases permeability of distal and collecting tubules to water→ urine concentration.
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