A 64-year-old female presents with central chest pain radiating down her left arm of 20 minutes duration.. IV GTN

A 64-year-old female presents with central chest pain radiating down her left arm of 20 minutes duration. On examination the pulse is 90 bpm and regular and the BP is 205/110 mmHg. ECG shows 2 mm ST elevation in leads V2-6. Morphine and aspirin have already been given.
What is the most appropriate next step?
A.A Observe
B.A IV streptokinase
C.A IV alteplase
D.A IV GTN***
E.A Temporary pacing.