A 49-year-old man with idiopathic pulmonary arterial hypertension has a negative acute vasodilator test.. Nifedipine

A 49-year-old man with idiopathic pulmonary arterial hypertension has a negative acute vasodilator test.
Which one of the following medications is least likely to be beneficial in his long-term management?
A.A Nifedipine***
B.A Treprostinil
C.A Bosentan
D.A Sildenafil
E.A Warfarin.
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