Dr. Samson prescribes didanosine (ddI [Videx]), 200 mg P.O. every 12 hours, for a client with acquired immunodeficiency syndrome (AIDS) who is intolerant to zidovudine (azidothymidine, AZT [Retrovir]). Which condition in the client’s history warrants cautious use of this drug?
a. Peripheral neuropathy
b. Diabetes mellitus
c. Hypertension
d. Asthma
Answer A. A history of peripheral neuropathy, renal or hepatic impairment, hyperuricemia, or pancreatitis warrants cautious use of didanosine because these disorders increase the risk of adverse effects.
Diabetes mellitus, hypertension, and asthma aren’t significant history findings for a client who is to receive didanosine.
a. Peripheral neuropathy
b. Diabetes mellitus
c. Hypertension
d. Asthma
Answer A. A history of peripheral neuropathy, renal or hepatic impairment, hyperuricemia, or pancreatitis warrants cautious use of didanosine because these disorders increase the risk of adverse effects.
Diabetes mellitus, hypertension, and asthma aren’t significant history findings for a client who is to receive didanosine.
