Autoimmune factors and autoimmune factors
The role of self-immunity in pregnancy loss has recently been heightened by the detection of autoantibodies and recurrent spontaneous miscarriages such as APA antibodies, anti-dsDNA antibodies, anticardiolipin antibodies (ACA), lupus anticoagulant antibodies (LA) and mitochondria Antimitochondrial antibodies (AMA) and antibodies ANA and others.
The role of autoimmune factors in recurrent pregnancy loss was recognized even in women without clinical signs of autoimmune diseases (Blumenfeld et al., 1991; Dudley & Branch, 1989). Attention to self-immunity has been a frequent cause of spontaneous abortion by detecting the association between APA, ACA and LA antibodies and recurrent pregnancy loss. It was noted that 10% of women who lost frequently had LA antibodies and 10-30% had ACA The majority of these women do not have self-protective symptoms (Dudley & Branch, 1989). In a study by Scott & Rote (1987), 242 pregnant women were performed, showing that 65% of women with APA (non-treatment) had a pregnancy loss or the death of their daughter. Self-immune diseases are attributed to different immune disorders that cause many tissue damage. In a normal state, the immune system can recognize and respond to antigens, but failure can lead to many pathological events and autoimmune diseases. Uncontrolled autoimmune diseases in pregnant women accompanied by APA, thrombtic events, and thrombocytopenia can be special risk factors that lead to loss of pregnancy (Frederickson & Wilkings -Haug, 1997). Both humoral immunity and cellular immunity can change during pregnancy, but there is no clear agreement on the nature of these changes. There is no definitive agreement on the effect of pregnancy on self-antibody production, where research has increased or decreased or may have reached Self - Immune Patients. While self-antibodies have been studied in women with symptoms associated with autoimmune diseases, few studies have focused on self-antibodies in pregnant women who do not have such symptoms. Among the problems that have been associated with previous studies is their lack of control groups, (Patterson et al., 1987), and that such antibodies are more frequent than those with normal pregnancies (Poluk et al., 1971; Meles et al., 1983; Farrom et al., 1984; Natural women who are not pregnant. The probability of developing autoimmune diseases during pregnancy (Peresellin, 1976) and changes in levels of self-antibodies during pregnancy can be attributed to the effect of steroid hormones or other factors on the immune system, but levels of antibodies generally do not change or rise slightly during Pregnancy (Kenney & Diamond, 1980).
The role of self-immunity in pregnancy loss has recently been heightened by the detection of autoantibodies and recurrent spontaneous miscarriages such as APA antibodies, anti-dsDNA antibodies, anticardiolipin antibodies (ACA), lupus anticoagulant antibodies (LA) and mitochondria Antimitochondrial antibodies (AMA) and antibodies ANA and others.
The role of autoimmune factors in recurrent pregnancy loss was recognized even in women without clinical signs of autoimmune diseases (Blumenfeld et al., 1991; Dudley & Branch, 1989). Attention to self-immunity has been a frequent cause of spontaneous abortion by detecting the association between APA, ACA and LA antibodies and recurrent pregnancy loss. It was noted that 10% of women who lost frequently had LA antibodies and 10-30% had ACA The majority of these women do not have self-protective symptoms (Dudley & Branch, 1989). In a study by Scott & Rote (1987), 242 pregnant women were performed, showing that 65% of women with APA (non-treatment) had a pregnancy loss or the death of their daughter. Self-immune diseases are attributed to different immune disorders that cause many tissue damage. In a normal state, the immune system can recognize and respond to antigens, but failure can lead to many pathological events and autoimmune diseases. Uncontrolled autoimmune diseases in pregnant women accompanied by APA, thrombtic events, and thrombocytopenia can be special risk factors that lead to loss of pregnancy (Frederickson & Wilkings -Haug, 1997). Both humoral immunity and cellular immunity can change during pregnancy, but there is no clear agreement on the nature of these changes. There is no definitive agreement on the effect of pregnancy on self-antibody production, where research has increased or decreased or may have reached Self - Immune Patients. While self-antibodies have been studied in women with symptoms associated with autoimmune diseases, few studies have focused on self-antibodies in pregnant women who do not have such symptoms. Among the problems that have been associated with previous studies is their lack of control groups, (Patterson et al., 1987), and that such antibodies are more frequent than those with normal pregnancies (Poluk et al., 1971; Meles et al., 1983; Farrom et al., 1984; Natural women who are not pregnant. The probability of developing autoimmune diseases during pregnancy (Peresellin, 1976) and changes in levels of self-antibodies during pregnancy can be attributed to the effect of steroid hormones or other factors on the immune system, but levels of antibodies generally do not change or rise slightly during Pregnancy (Kenney & Diamond, 1980).
Labels
abortion