Alloimmune factors and abortion
The antigen of the fetus is rejected by the mother's immune system. Protection from this effect has been assumed by many researchers to include the presence of a maternal blocking factor (IgG) that covers the foreign antigen, preventing the fetus from The researchers have shown that women with frequent spontaneous abortions may lack such a closure factor (Coulam & Hemenway, 1999; Chong et al., 1995).
Many studies have not demonstrated the role of HLA in making the mother's immune system fail to produce clogged antibodies,
There was no difference between the degree of HLA antigen in couples with frequent spontaneous miscarriages and control groups. A prenatal and postpartum follow-up study was performed on couples with recurrent miscarriage who found no differences in the extent of HLA contribution among couples who later succeeded in pregnancy As well as their inability to demonstrate an increase in the production of immunosuppressive agents against the HLA of the fetus after birth in both these women and the control group (Caudle et al., 1983). Stays et al. (1997) found that a group of women with spontaneous miscarriages reported that women who had leukocytes had more chances (78%) than did women who had their own white pellets and were not receiving treatment Others (37%). In a study by Smith & Cowchock (1988), by injecting women with frequent spontaneous miscarriages, the chances of successful pregnancy were only 50%. In another study involving 15 research centers, the researchers noted an increase in the proportion of births from 60-70% in the group treated with Paternal Leukocyte Immunization (PLI) (Stites et al., 1997).
The antigen of the fetus is rejected by the mother's immune system. Protection from this effect has been assumed by many researchers to include the presence of a maternal blocking factor (IgG) that covers the foreign antigen, preventing the fetus from The researchers have shown that women with frequent spontaneous abortions may lack such a closure factor (Coulam & Hemenway, 1999; Chong et al., 1995).
Many studies have not demonstrated the role of HLA in making the mother's immune system fail to produce clogged antibodies,
There was no difference between the degree of HLA antigen in couples with frequent spontaneous miscarriages and control groups. A prenatal and postpartum follow-up study was performed on couples with recurrent miscarriage who found no differences in the extent of HLA contribution among couples who later succeeded in pregnancy As well as their inability to demonstrate an increase in the production of immunosuppressive agents against the HLA of the fetus after birth in both these women and the control group (Caudle et al., 1983). Stays et al. (1997) found that a group of women with spontaneous miscarriages reported that women who had leukocytes had more chances (78%) than did women who had their own white pellets and were not receiving treatment Others (37%). In a study by Smith & Cowchock (1988), by injecting women with frequent spontaneous miscarriages, the chances of successful pregnancy were only 50%. In another study involving 15 research centers, the researchers noted an increase in the proportion of births from 60-70% in the group treated with Paternal Leukocyte Immunization (PLI) (Stites et al., 1997).
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abortion