Regarding VSD , the following are correct except.. Eisenmenger syndrome can develop by the end of the first year of life

Regarding VSD , the following are correct except:
May close spontaneously in the muscular type.
May be presented by aortic regurge.
Is liable to infective endocarditis.
Eisenmenger syndrome can develop by the end of the first year of life.***
Is common in patients with down syndrome. (the most common).
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