RCT contraindicated in.. Vertical fracture of root

RCT contraindicated in:
a. Vertical fracture of root. ***
b. Diabetic Pt.
c. Unrestored teeth.
d. Periodontally involved teeth.
Gutta percha contain 20% gutta percha(matrix).66% zinc oxide(filler),11% heavy metal sulfates(radiopacifier).