25 year old Female in her First Trimester of Pregnancy Presents with an Acute dental infection, Which of the following is CONTRAINDICATED for this patient:
1- Prescription of a radiograph.
2- Prescription of penicillin V.
3- Extraction using 2% xylocaine with 1:100,000 epinephrine.
4- Acetylsalicylic acid for pain management.
5- Aspirin cause teratogenic effects in first trimester***
Taking medication during pregnancy is never trivial! Thus, even anti-inflammatories such as aspirin or ibuprofen can be dangerous. They should be avoided from the sixth month of pregnancy. Future moms, discover without delay the specialties involved and our advice to limit the risks.
Taking medication during pregnancy can be dangerous for the mother or baby. Indeed, several data indicate that a large number of pregnant women take nonsteroidal anti-inflammatory drugs (NSAIDs), despite the contraindications mentioned in the marketing authorizations (MAs). NSAIDs often prescribed or used for self-medication.
In a press release published on January 26, 2017, the National Agency for the Safety of Medicines and Health Products (ANSM) reminds pregnant women, their families, and all health professionals that these drugs are formally contraindicated from the beginning of the 6th month of pregnancy.
Which nonsteroidal anti-inflammatory drugs are contraindicated during pregnancy?
Even taken punctually, anti-inflammatory drugs are to be banned beyond 24 weeks of amenorrhea (6 months of pregnancy). And this, whether on prescription or over-the-counter, regardless of the duration of treatment and the route of administration: including oral, injectable, and cutaneous.
This concerns in particular:
- Aspirin.
- Ibuprofen.
- The anticox2.
And all medicines called "nonsteroidal anti-inflammatory drugs" (NSAIDs).
These are commonly used to treat fever, dental pain, relieve headaches, back pain ... and many other health problems. And most are over-the-counter.
Nonsteroidal anti-inflammatory drugs: what risks for baby?
It is essential to respect these recommendations, and not to take NSAIDs from the sixth month of pregnancy. Because these specialties can cause serious problems in baby:
- Heart failure.
- Renal failure.
- In-utero death (extreme cases).
Also, even if you have taken one of these drugs only once, it is imperative to prevent and consult very quickly your gynecologist. Only he can decide what to do.
Ibuprofen to proscribe early in pregnancy:
If the ANSM emphasizes the risk of NSAIDs for the fetus from the 6th month of pregnancy, ibuprofen should be banned from the beginning of pregnancy.
A study carried out by Inserm, published in March 2017, showed that this molecule can lead to disturbances of the hormonal system in the testis of the fetus with possible consequences on the development of the male urogenital tract. Indeed, "this drug suppresses the production of different testicular hormones, including testosterone, which controls the primary and secondary sexual characteristics and descent of the testes.These effects are achieved at doses similar to the conventional dosage."
For the authors of the study, "there is a window of sensitivity specific during the first trimester of development of the fetus during which ibuprofen presents, it seems, a risk for the future genital and reproductive system of the all clusters of cues converge to great caution about the use of this drug in the first trimester of pregnancy.In addition, if we take into account the body of data available, it appears that the taking several analgesics during pregnancy represents an even greater danger for the hormonal balance of the male fetus. "
Ibuprofen would have the same effect on the fertility of unborn girls. A study conducted by Inserm researchers, published in February 2018, reveals that prolonged intake of ibuprofen during the first 24 weeks of pregnancy would reduce the stock of eggs in the female fetus. "Two to seven days of taking ibuprofen during the first trimester of pregnancy significantly reduces egg production in the ovaries of the female fetus," says Dr. Séverine Mazaud-Guittot, author of the study. She requested that recommendations for taking ibuprofen during pregnancy be reviewed. Today, pregnant women are advised not to take it after the first three months of pregnancy because it increases the risk of fetal malformations. But these studies show that the dangers exist from the first weeks with important consequences on the fertility of the child in adulthood.
Pains during pregnancy: the importance of adapting your treatment:
Whatever your pathology, the ANSM stresses that it is essential to reevaluate any drug treatment during pregnancy. The Agency states that until the 5th month of pregnancy, NSAIDs should only be used when essential, at the lowest effective dose and for the shortest duration.
In any case, only your doctor may prescribe non-steroidal anti-inflammatory drugs after the 6th month. And do not forget: ask your doctor or pharmacist for advice before taking any medicine.
Note that there are drug and non-drug alternatives, regardless of the term of pregnancy.
Taking medication during pregnancy is never trivial! Thus, even anti-inflammatories such as aspirin or ibuprofen can be dangerous. They should be avoided from the sixth month of pregnancy. Future moms, discover without delay the specialties involved and our advice to limit the risks.
Taking medication during pregnancy can be dangerous for the mother or baby. Indeed, several data indicate that a large number of pregnant women take nonsteroidal anti-inflammatory drugs (NSAIDs), despite the contraindications mentioned in the marketing authorizations (MAs). NSAIDs often prescribed or used for self-medication.
In a press release published on January 26, 2017, the National Agency for the Safety of Medicines and Health Products (ANSM) reminds pregnant women, their families, and all health professionals that these drugs are formally contraindicated from the beginning of the 6th month of pregnancy.
Which nonsteroidal anti-inflammatory drugs are contraindicated during pregnancy?
Even taken punctually, anti-inflammatory drugs are to be banned beyond 24 weeks of amenorrhea (6 months of pregnancy). And this, whether on prescription or over-the-counter, regardless of the duration of treatment and the route of administration: including oral, injectable, and cutaneous.
This concerns in particular:
- Aspirin.
- Ibuprofen.
- The anticox2.
And all medicines called "nonsteroidal anti-inflammatory drugs" (NSAIDs).
These are commonly used to treat fever, dental pain, relieve headaches, back pain ... and many other health problems. And most are over-the-counter.
Nonsteroidal anti-inflammatory drugs: what risks for baby?
It is essential to respect these recommendations, and not to take NSAIDs from the sixth month of pregnancy. Because these specialties can cause serious problems in baby:
- Heart failure.
- Renal failure.
- In-utero death (extreme cases).
Also, even if you have taken one of these drugs only once, it is imperative to prevent and consult very quickly your gynecologist. Only he can decide what to do.
Ibuprofen to proscribe early in pregnancy:
If the ANSM emphasizes the risk of NSAIDs for the fetus from the 6th month of pregnancy, ibuprofen should be banned from the beginning of pregnancy.
A study carried out by Inserm, published in March 2017, showed that this molecule can lead to disturbances of the hormonal system in the testis of the fetus with possible consequences on the development of the male urogenital tract. Indeed, "this drug suppresses the production of different testicular hormones, including testosterone, which controls the primary and secondary sexual characteristics and descent of the testes.These effects are achieved at doses similar to the conventional dosage."
For the authors of the study, "there is a window of sensitivity specific during the first trimester of development of the fetus during which ibuprofen presents, it seems, a risk for the future genital and reproductive system of the all clusters of cues converge to great caution about the use of this drug in the first trimester of pregnancy.In addition, if we take into account the body of data available, it appears that the taking several analgesics during pregnancy represents an even greater danger for the hormonal balance of the male fetus. "
Ibuprofen would have the same effect on the fertility of unborn girls. A study conducted by Inserm researchers, published in February 2018, reveals that prolonged intake of ibuprofen during the first 24 weeks of pregnancy would reduce the stock of eggs in the female fetus. "Two to seven days of taking ibuprofen during the first trimester of pregnancy significantly reduces egg production in the ovaries of the female fetus," says Dr. Séverine Mazaud-Guittot, author of the study. She requested that recommendations for taking ibuprofen during pregnancy be reviewed. Today, pregnant women are advised not to take it after the first three months of pregnancy because it increases the risk of fetal malformations. But these studies show that the dangers exist from the first weeks with important consequences on the fertility of the child in adulthood.
Pains during pregnancy: the importance of adapting your treatment:
Whatever your pathology, the ANSM stresses that it is essential to reevaluate any drug treatment during pregnancy. The Agency states that until the 5th month of pregnancy, NSAIDs should only be used when essential, at the lowest effective dose and for the shortest duration.
In any case, only your doctor may prescribe non-steroidal anti-inflammatory drugs after the 6th month. And do not forget: ask your doctor or pharmacist for advice before taking any medicine.
Note that there are drug and non-drug alternatives, regardless of the term of pregnancy.
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