Juvenile hyaline fibromatosis.. Disturbance in the manufacture of glycosaminoglycans. Small papules or nodules

Juvenile hyaline fibromatosis:
Is a disorder in the manufacture of glycosaminoglycans.
Clinical manifestations:
- Skin lesions appear at birth or occur in early childhood. There may be papules or small pearling nodules, especially on the face and neck. Massive subcutaneous tumors may also occur.
- Tumors may be stiff or soft, moving or steady, and may be ulcerated.
- Gingival hyperplasia is commonly found, and contractions in the fingers, elbows, hips, and knees may occur.
- Pests The condition of the bone may occur in the cranium, long bones and salts leading to articular contractions.
- Muscles may develop poorly.
- Histological changes show the insertion of a non-characteristic hyaline (glazed) material. The condition may persist until puberty, leading to articular contractions and impotence.

HPV infection occurs when the virus enters the body, usually through a wound, scratch, or small cut in the skin. The virus is transmitted mainly through contact with the skin.
HPV infection occurs in the genitals through sex, anal sex, and skin contact in the genital area. Some cases of human papillomavirus infection caused by oral or upper respiratory tract infections are transmitted through oral sex.
If you are pregnant and have HPV infection with genital warts, the size of the warts may increase and multiply during pregnancy. Treatment is likely to be suspended for a period until after delivery.
Large genital warts can block the birth canal, causing complications of vaginal delivery. Infection may be associated with rare and non-cancerous growth in the child's throat (larynx).
Warts are contagious. They spread through contact with a wart or something that has touched the wart.
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