Bile salts are very important in all stages of long chain fat digestion:
Emulsification: The bile salts (rinse) proteins suspended with fat after food exposure to the effect of Pepsin.
Salicylic acid: The bile salts prepare the appropriate medium for the work of lipase (pH = 9). The lipase does not work without bile salts.
Water solubility with syringes: Bile salts are the most important component of the salts.
If: liver diseases that cause bile stasis cause fatty diarrhea due to lack of digestion of fat due to lack of bile salts.
Base: No bile salts → No fat digestion.
Note: The bile salts used in the previous stages of digestion do not occur with the stool, but are re-absorbed 90% of them before the end of the ileum where re-used.
However, in some cases, such as Crohn's disease, lymphoma, tuberculosis, there is a defect in the ileum (or when the ileum is removed). The absorption of the bile salts leads to colonization, which leads to diarrhea and thus a watery diarrhea. As a result of the deficiency of bile salts (which can not be re-absorbed), there will be a defect in digestion and absorption of fat, resulting in seborrheic diarrhea, and then the emergence of symptoms resulting from lack of absorption of fat, such as weight loss and lack of absorption of vitamins KEDA.
That is, when the eradication of the ileum occurs water diarrhea first and then another Shi diarrhea occurs fatty (an important question Kti, especially the sixth interview)
Medium-chain fat (8-12 carbon atoms):
- Do not go through all the previous stages as it absorbs directly without change to the portal rotation.
- This can be used clinically in some disorders such as impaired absorption at the level of lymph vessels or intestinal defects or bile stasis (anything that hinders stages of long-chain fat absorption), the patient is replaced with medium chain fat (such as palm oil).
- Medium-chain fat does not need the necessary bile salts in the long-chain lipid digestion stages (therefore useful for long-term chronic bronchial stenosis).
Emulsification: The bile salts (rinse) proteins suspended with fat after food exposure to the effect of Pepsin.
Salicylic acid: The bile salts prepare the appropriate medium for the work of lipase (pH = 9). The lipase does not work without bile salts.
Water solubility with syringes: Bile salts are the most important component of the salts.
If: liver diseases that cause bile stasis cause fatty diarrhea due to lack of digestion of fat due to lack of bile salts.
Base: No bile salts → No fat digestion.
Note: The bile salts used in the previous stages of digestion do not occur with the stool, but are re-absorbed 90% of them before the end of the ileum where re-used.
However, in some cases, such as Crohn's disease, lymphoma, tuberculosis, there is a defect in the ileum (or when the ileum is removed). The absorption of the bile salts leads to colonization, which leads to diarrhea and thus a watery diarrhea. As a result of the deficiency of bile salts (which can not be re-absorbed), there will be a defect in digestion and absorption of fat, resulting in seborrheic diarrhea, and then the emergence of symptoms resulting from lack of absorption of fat, such as weight loss and lack of absorption of vitamins KEDA.
That is, when the eradication of the ileum occurs water diarrhea first and then another Shi diarrhea occurs fatty (an important question Kti, especially the sixth interview)
Medium-chain fat (8-12 carbon atoms):
- Do not go through all the previous stages as it absorbs directly without change to the portal rotation.
- This can be used clinically in some disorders such as impaired absorption at the level of lymph vessels or intestinal defects or bile stasis (anything that hinders stages of long-chain fat absorption), the patient is replaced with medium chain fat (such as palm oil).
- Medium-chain fat does not need the necessary bile salts in the long-chain lipid digestion stages (therefore useful for long-term chronic bronchial stenosis).
Labels
Digestive endothelium