- Colchicine:
It is found in plants of the type of "Kulchikum Atomnal" and is in the form of blocks of glue or crystals or powders or yellow flakes are very toxic; used in medicine.
For what conditions or diseases is this medication prescribed?
Colchicine is used to prevent gout attacks (sudden and severe pain in one or more joints, caused by abnormally high levels of a substance called uric acid in the blood) in adults. Colchicine (Colcrys) is also used to relieve the pain of gout attacks when they occur. Colchicine (Colcrys) is also used to treat familial Mediterranean fever (FMF; an innate condition that causes episodes of fever, pain and swelling of the stomach area, lungs and joints in adults and children over 4 years of age. Colchicine It is not a pain reliever and cannot be used to treat pain that is not caused by gout or FMF. Colchicine belongs to a class of medications called anti-gout agents. It works by stopping the natural processes that cause inflammation and other symptoms of gout and FMF
How should this medicine be used?
The presentation of colchicine is in a tablet and solution (liquid; Gloperba) to take by mouth, with or without food. When colchicine is used to prevent gout attacks or to treat FMF, it is usually taken once or twice a day. When colchicine (Colcrys) is used to relieve the pain of a gout attack, a dose is usually taken at the first sign of pain and a smaller second dose is usually taken an hour later. If you do not experience relief or have another attack several days after treatment, talk to your doctor before taking additional doses of the medication. Follow the instructions on the label of your prescription carefully and ask your doctor or pharmacist to explain any part you do not understand. Take colchicine exactly as directed. Do not take a greater or lesser amount of the medicine, or take it more often than your doctor's prescription indicates.
It is important to use an oral syringe (measuring device) to accurately measure the correct amount of fluid for each dose; Do not use a house spoon.
If you are taking colchicine (Colcrys) to treat FMF, your doctor may start with a low dose and gradually increase it. Your doctor may decrease your dose if you experience side effects.
If you are taking colchicine to prevent gout attacks, call your doctor immediately if you experience a gout attack during your treatment. Your doctor may tell you to take an additional dose of colchicine, followed by a smaller dose one hour later. If you take additional doses of colchicine to treat a gout attack, you should not take the next scheduled dose of colchicine until at least 12 hours have elapsed since you took the additional doses.
Colchicine can prevent gout attacks and control FMF only while taking the medication. Continue to take colchicine even if you feel well. Do not stop taking colchicine without talking to your doctor.
What other uses does this medication have?
This medicine may be prescribed for other uses. Ask your doctor or pharmacist for more information.
What special precautions should I follow?
It is found in plants of the type of "Kulchikum Atomnal" and is in the form of blocks of glue or crystals or powders or yellow flakes are very toxic; used in medicine.
For what conditions or diseases is this medication prescribed?
Colchicine is used to prevent gout attacks (sudden and severe pain in one or more joints, caused by abnormally high levels of a substance called uric acid in the blood) in adults. Colchicine (Colcrys) is also used to relieve the pain of gout attacks when they occur. Colchicine (Colcrys) is also used to treat familial Mediterranean fever (FMF; an innate condition that causes episodes of fever, pain and swelling of the stomach area, lungs and joints in adults and children over 4 years of age. Colchicine It is not a pain reliever and cannot be used to treat pain that is not caused by gout or FMF. Colchicine belongs to a class of medications called anti-gout agents. It works by stopping the natural processes that cause inflammation and other symptoms of gout and FMF
How should this medicine be used?
The presentation of colchicine is in a tablet and solution (liquid; Gloperba) to take by mouth, with or without food. When colchicine is used to prevent gout attacks or to treat FMF, it is usually taken once or twice a day. When colchicine (Colcrys) is used to relieve the pain of a gout attack, a dose is usually taken at the first sign of pain and a smaller second dose is usually taken an hour later. If you do not experience relief or have another attack several days after treatment, talk to your doctor before taking additional doses of the medication. Follow the instructions on the label of your prescription carefully and ask your doctor or pharmacist to explain any part you do not understand. Take colchicine exactly as directed. Do not take a greater or lesser amount of the medicine, or take it more often than your doctor's prescription indicates.
It is important to use an oral syringe (measuring device) to accurately measure the correct amount of fluid for each dose; Do not use a house spoon.
If you are taking colchicine (Colcrys) to treat FMF, your doctor may start with a low dose and gradually increase it. Your doctor may decrease your dose if you experience side effects.
If you are taking colchicine to prevent gout attacks, call your doctor immediately if you experience a gout attack during your treatment. Your doctor may tell you to take an additional dose of colchicine, followed by a smaller dose one hour later. If you take additional doses of colchicine to treat a gout attack, you should not take the next scheduled dose of colchicine until at least 12 hours have elapsed since you took the additional doses.
Colchicine can prevent gout attacks and control FMF only while taking the medication. Continue to take colchicine even if you feel well. Do not stop taking colchicine without talking to your doctor.
What other uses does this medication have?
This medicine may be prescribed for other uses. Ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking colchicine,
- tell the doctor and pharmacist if you are allergic to colchicine, any other medicine or any of the ingredients in the tablets or colchicine solution. Ask your doctor or pharmacist or check the medication guide for a list of ingredients.
- Tell your doctor and pharmacist about what other prescription and non-prescription medications, vitamins and nutritional supplements you are taking, have taken during the last 14 days or plan to take. Be sure to mention any of the following: antibiotics such as azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin); telithromycin (Ketek; not available in the U.S.); antifungal medications such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), and posaconazole (Noxafil); aprepitant (Emend); certain cholesterol-lowering medications (statins) such as atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), and simvastatin (Zocor); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Digitek, Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac, others); fibrates such as bezafibrate, fenofibrate (Antara, Lipofen), and gemfibrozil (Lopid); HIV or AIDS medications such as amprenavir (Agenerase), atazanavir (Reyataz), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (in Kaletra, Norvir), and saquinavir (Invirase); nefazodone; ranolazine (Ranexa); and Verapamil (Calan, Covera, Isoptin, Verelan). Your doctor may need to change the doses of your medications or monitor you closely to see if you have side effects. Many other medications may also interact with colchicine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- Tell your doctor if you have or have had liver disease. Your doctor will probably tell you not to take colchicine if you are taking any other medications or if you have kidney and liver disease.
- Tell your doctor if you are pregnant, plan to become pregnant or are breastfeeding. If you become pregnant while taking colchicine, call your doctor.
What special diet should I follow while I take this medicine?
Do not eat grapefruit or drink grapefruit juice during your colchicine treatment.
What do I have to do if I forget to take a dose?
Take the missed dose as soon as you remember. If you are taking colchicine on a regular basis and it is almost time for the next dose, skip the dose you did not take and continue with your regular dosing schedule. Do not double the dose to make up for the missed dose.
However, if you are taking colchicine (Colcrys) to treat a gout attack that occurred while taking colchicine to prevent gout attacks and forgot to take the second dose, take the missed dose as soon as you remember. Then, wait at least 12 hours before taking your next scheduled dose of colchicine.
What are the side effects that this medicine could cause?
Colchicine may cause side effects. Tell your doctor if any of the following symptoms are severe or do not go away:
nausea
- vomiting
- diarrhea
- stomach pain or cramps
Some Side Effects Can Be Serious. If you experience any of the following symptoms, stop taking colchicine and call your doctor immediately:
- muscle pain or weakness
- numbness or tingling in the fingers or toes
- unusual bleeding or bruising
- sore throat, fever, chills or other symptoms of infection
- tiredness or weakness
- pale or gray color of the lips, tongue or palms
Colchicine may decrease fertility in men. Talk to your doctor about the risks of taking colchicine.
How should I store or dispose of this medicine?
Keep this medicine in its original container, tightly closed and out of the reach of children. Store it at room temperature and away from excess heat and moisture (do not store it in the bathroom).
It is important that you keep all medications out of the sight and reach of children, because many containers (such as weekly pill boxes, and those containing ophthalmic drops, creams, patches and inhalers) are not proof of small children, who can easily open them. In order to protect them from intoxication, always wear safety covers and immediately place medications in a safe place, one that is up and away from your sight and reach. http://www.upandaway.org/es/
Medications that are no longer needed should be disposed of in an appropriate manner to ensure that pets, children and others cannot consume them. However, you should not discard these medications by the toilet. Instead, the best way to get rid of your medications is through a medication return program. Talk to your pharmacist or contact your local trash / recycling department to learn about your community's drug return programs. See the Food and Drug Administration (FDA) website (https://goo.gl/xRXbPn) for more information on how to safely dispose of medications if you do not have access to the medication return program.
what should I do in case of an overdose?
In case of overdose, go immediately to the nearest hospital emergency room. Taking too much colchicine can cause death.
Symptoms of overdose may include:
- stomach ache
nausea
- vomiting
- diarrhea
- unusual bleeding or bruising
- sore throat, fever, chills or other symptoms of infection
- pale or gray color of the lips, tongue or palms
slow breathing
- slow or stopped heartbeat
What other important information should I know?
Attend all appointments with your doctor and the laboratory. Your doctor may order some laboratory tests to check your response to colchicine.
Do not let anyone else use your medicine. Ask your pharmacist any questions you have about refilling your prescription.
It is important that you keep a written list of all the medications you are taking, including those you received with a prescription and those you bought without a prescription, including vitamins and diet supplements. You should have the list every time you visit your doctor or when you are admitted to a hospital. It is also important information in emergencies.
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