This mechanism is the basis for the work of all sulfonil urea drugs. Insulin secretion is stimulated from beta cells by combining these drugs with receptors on beta cells.
The combination of these drugs in this way prevents the release of potassium ions through the channels, resulting in the disappearance of polarization depolarization.
This in turn opens the calcium channels and leads to the entry of calcium and the release of insulin ready from within the cells.
The theory confirms that these drugs are ineffective in patients who lack the presence of insulin or even animals in which beta cells were destroyed using the chemical alloxan.
The combination of these drugs in this way prevents the release of potassium ions through the channels, resulting in the disappearance of polarization depolarization.
This in turn opens the calcium channels and leads to the entry of calcium and the release of insulin ready from within the cells.
The theory confirms that these drugs are ineffective in patients who lack the presence of insulin or even animals in which beta cells were destroyed using the chemical alloxan.
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SULFONYL UREA DRUGS