As an antiarrhythmic drug, procainamide is most similar in action to which one of the following agents.. Quinidine As an antiarrhythmic drug , procainamide is most similar in action to which one of the following agents? A) Amiodarone B) Propranolol C) Digoxin D) Verapamil E) Quinidine*** Share This: Facebook Twitter Google+ Stumble Digg Email ThisBlogThis!Share to XShare to Facebook