all cause false –v ABO blood grouping except - prothrompin time detect

- all cause  false –v ABO blood grouping except:
Too short incubation***

- prothrompin time detect:
Extrinsic pathway of coagulation***

In the prothrombin time test, the time required to form a fibroin clot in a plasma sample was added. Citrate was added after the addition of calcium ions and thromboplastin to the factor III.
Prothrombin (Prothrombin) is a protein produced in the liver, the underlying substance that produces coagulation factors that help clotting blood, among them.
Prothrombin itself is not effective, but with the addition of other factors found in the plasma or that can be artificially added to the test tube, prothrombin is converted into thrombin.
Thrombin is an enzyme that converts fibrinogen (fibrinogen) to fibrin, which is actually a thrombolytic substance.
This test practically examines all the coagulation routes, usually used to test the effect of anticoagulants given orally.
Today, the test result of prothrombin time is given by calculating this time compared to the international standardized INR (International Normalized Ratio).

Reasons for testing:
This test is conducted to investigate the effect of anti-coagulants (blood anticoagulants) in the prevention of blood clots and to help detect and diagnose haemorrhagic disorders.
If the patient is using an anticoagulant, the doctor will check the global measured rate and the time of the prothrombin PT / INR regularly to ensure that the drug is working properly and that the values ​​of these two tests are appropriate for the patient's condition.
The doctor continues to retest until the desired effect is achieved without causing severe bleeding or bruising, without a specific duration or frequency of re-measurement.
Prothrombin can be measured when the patient, who does not take anticoagulants, has signs or symptoms of a hemorrhagic disorder, ranging from haemorrhaging, gingivitis, bruising, heavy menstrual cycles, blood in the stool or urine, and even arthritic symptoms Joints) and vision deficiency and chronic anemia.
Prothrombin time can sometimes be required when a patient is about to undergo a medical procedure, such as surgery, to ensure the natural ability to clot.

The test can be used to help diagnose inherited disorders and other conditions that may affect blood clotting. These include:
- Vitamin K deficiency
- Deficiency factor I, II, V, VII or X.
- Liver diseases.
- Hemophilia is a disease in the blood.
- Problems with bone marrow.
- Von Wilbrand Disease.
- Problems with the immune system.
- Some cancers, including leukemia.
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