Surfactant not used orally:
a- Na lauryl sulphate.***
b- Tween.
c- Span.
Sodium Lauryl Sulfate:
Pharmaceutical use:
Surface active negative agent, detergent, emulsifying agent, transdermal window material, lubricant in compactor and capsule, moisturizer.
Sodium lauryl sulfate is widely used in non-injectable pharmaceutical forms and cosmetics, as a surfactant with a negative charge.
It also plays a clean and moisturizing role in all acidic and alkaline environments.
Effect on body health:
This substance is widely used in cosmetics and topical and oral preparations, as it is a medium toxic substance characterized by severe toxic effects including scratching the eye, skin, mucous membranes, upper respiratory tract and stomach.
Repeated repeated exposure to sodium lauryl sulfate solutions may lead to skin dryness and cracking, which may later develop into contact dermatitis. Continuous inhalation of this substance will harm the lungs. Pneumonia can cause dysfunction of airway hyperactivity and pulmonary allergic reactions.
Studies conducted on animals during the injection of this substance have shown a clear lung toxicity in the lungs, liver and kidney.
When the effect of this substance on the bacteria was tested, the test result was negative.
Side effects of sodium lauryl sulfate when used in cosmetics and pharmaceutical forms are mainly related to skin or eye irritation, which occurs after the topical application of these preparations. Caution should be given to sodium lauryl sulphate ruida. Finally, the potential lethal dose in humans is 0.5-5 g / kg bw.
- LD50 (mouse, IP) = 0.25 g / kg.
- LD50 (mouse, IV) = 0.12 g / kg.
- LD50 (rat, oral) = 1.29 g / kg.
- LD50 (rat, IP) = 0.21 g / kg.
- LD50 (rat, IV) = 0.12 g / kg.
Safety Usage:
The precautions used in dealing with the material vary depending on the quantity and the surrounding conditions.
Avoid inhalation or contact with skin and eyes.
It is also recommended to protect the eye and wear gloves and other protective clothing according to the surrounding conditions. In addition, it is necessary to ensure adequate ventilation or wearing a protective mask from dust and avoid repeated exposure to this material.
Sodium lauryl sulfate has been shown to be toxic when it burns.
a- Na lauryl sulphate.***
b- Tween.
c- Span.
Sodium Lauryl Sulfate:
Pharmaceutical use:
Surface active negative agent, detergent, emulsifying agent, transdermal window material, lubricant in compactor and capsule, moisturizer.
Sodium lauryl sulfate is widely used in non-injectable pharmaceutical forms and cosmetics, as a surfactant with a negative charge.
It also plays a clean and moisturizing role in all acidic and alkaline environments.
Effect on body health:
This substance is widely used in cosmetics and topical and oral preparations, as it is a medium toxic substance characterized by severe toxic effects including scratching the eye, skin, mucous membranes, upper respiratory tract and stomach.
Repeated repeated exposure to sodium lauryl sulfate solutions may lead to skin dryness and cracking, which may later develop into contact dermatitis. Continuous inhalation of this substance will harm the lungs. Pneumonia can cause dysfunction of airway hyperactivity and pulmonary allergic reactions.
Studies conducted on animals during the injection of this substance have shown a clear lung toxicity in the lungs, liver and kidney.
When the effect of this substance on the bacteria was tested, the test result was negative.
Side effects of sodium lauryl sulfate when used in cosmetics and pharmaceutical forms are mainly related to skin or eye irritation, which occurs after the topical application of these preparations. Caution should be given to sodium lauryl sulphate ruida. Finally, the potential lethal dose in humans is 0.5-5 g / kg bw.
- LD50 (mouse, IP) = 0.25 g / kg.
- LD50 (mouse, IV) = 0.12 g / kg.
- LD50 (rat, oral) = 1.29 g / kg.
- LD50 (rat, IP) = 0.21 g / kg.
- LD50 (rat, IV) = 0.12 g / kg.
Safety Usage:
The precautions used in dealing with the material vary depending on the quantity and the surrounding conditions.
Avoid inhalation or contact with skin and eyes.
It is also recommended to protect the eye and wear gloves and other protective clothing according to the surrounding conditions. In addition, it is necessary to ensure adequate ventilation or wearing a protective mask from dust and avoid repeated exposure to this material.
Sodium lauryl sulfate has been shown to be toxic when it burns.
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pharmacology