Wednesday, February 22, 2023

Symptoms of vitamin B12 deficiency.. Weight loss. Sores on the tongue. Pernicious anemia and mental and neurological disorders



Symptoms of vitamin B12 deficiency.

  • General weakness with weight loss.
  • Sores on the tongue.
  • Tingling in the limbs.
  • Chill in the feeling.
In a sign of vitamin B12 deficiency and this lack of cases is acute lead to pernicious anemia and mental and neurological disorders are complex and further deterioration of the situation of the spinal cord.

Is B12 neuropathy permanent?


Long-term vitamin B12 deficiency can cause nerve damage. This may be permanent if you do not start treatment within 6 months of when your symptoms begin. Vitamin B12 deficiency anemia most often responds well to treatment. It will likely get better when the underlying cause of the deficiency is treated.

What vitamin deficiency causes tongue problems?

A common oral effect of vitamin B deficiency is a burning sensation in the mouth, especially on the tongue. People with this deficiency can also have trouble swallowing. The tongue may feel swollen. The tissue of the inner cheeks can be pale and may break apart easily and slough off.

Does pernicious anemia cause sore tongue?

Gastrointestinal symptoms

Approximately 50% of patients with pernicious anemia develop atrophic glossitis, presenting with a smooth tongue that may be painful and beefy red, with loss of papillae that is usually most marked along the edges of the tongue.

What does B12 deficiency tongue look like?

Clinical Findings in Tongue Pathology

B12 deficiency will also make the tongue sore and beefy-red in color. Glossitis, by causing swelling of the tongue, may also cause the tongue to appear smooth.

Can vitamin B12 deficiency cause altered mental status?

Vitamin B12 deficiency has been highly linked to several psychiatric disorders like impaired memory, irritability, depression, dementia, delirium, schizophrenia and psychosis1. Other commonly associated neurological disorders include paraesthesias, numbness and sub acute combined degeneration of the spinal cord2.

What organs does B12 deficiency affect?

Major organ systems affected include the blood, bone marrow and nervous system. Megaloblastic anemia results from a defect in thymidine and therefore DNA synthesis in rapidly dividing cells. Nervous system involvement is varied, some of which results from defective myelin synthesis and repair.

What are the psychological effects of B12 deficiency?

Deficiency of Vitamin B12 can result in hematological changes, neurological and psychiatric problems, which can manifest as irritability, changes in personality, depression, and memory loss [9]. It is also known to worsen depression by excitotoxic reactions caused by the accumulation of homocysteine [10].

How long does it take to recover from neurological symptoms from B12 deficiency?

All patients with neurological symptoms of vitamin B12 deficiency recovered within one month after vitamin B12 supplementation.

How long does it take to recover from B12 deficiency neuropathy?

Recovery from vitamin B12 deficiency takes time. You may not have any improvement during the first few months of treatment. Improvement may be gradual and may continue for up to six to 12 months.

What does the tongue look like with pernicious anemia?

Pernicious anemia causes the tongue's surface to look smooth and appear red instead of the pinkish color of a normal tongue. The tongue might also appear thick or beefy in texture. Some tongues might even be swollen or seem to have cracks.

Can B12 cause neuropathy?

B12 deficiency may cause demyelination of nerves in the peripheral and central nervous system13 and has been associated with peripheral neuropathy, loss of sensation in peripheral nerves, and weakness in lower extremities in older adults1, 1416.

How does B12 deficiency affect weight?

A Vitamin B12 deficiency can lead to long-term weight control problems. When the body's natural balance is disrupted, it typically responds by slowing down your metabolism, conserving fat stores, and burning fewer calories throughout the day.

Is weight loss a symptom of B12 deficiency?

Decreased appetite and weight loss. As a result of digestive problems, such as nausea, people with vitamin B-12 deficiency may lose their appetite. A decreased appetite can lead to weight loss in the long term.

What Vitamin has deficiency on nervous system disorders and pernicious anemia?


Long-term low vitamin B12 levels caused by pernicious anemia can affect your nervous system. Symptoms of potential nervous system problems include: Confusion. Short-term memory loss.

Can vitamin B12 deficiency affect your tongue?

Symptoms of vitamin B12 deficiency

a sore and red tongue (glossitis) mouth ulcers. pins and needles (paraesthesia)