The peripheral chemoreceptors are located at the level of the carotids and the aorta forming the carotid and aortic glomus.
The information from the corpuscles borrows the afferents from the Hering nerve then glossopharyngeal for the first and from the Cyon nerve then Vague for the second.
The frequency of action potentials in these afferent pathways is increased in the event of a decrease in the partial pressure of O2 in the blood, an increase in that of carbon dioxide or during acidification of the blood.
If reverse changes in blood gas occur, the frequency of action potentials will on the contrary be decreased.