A decrease in the effectiveness of the body's immune system
The main reason for a first type of sugar to the lack of efficiency of the body's immune system And accompanied by the appearance of antibodies (Antibodies ) Attack proteins insulin and cells Langer Hans and cause damage to the beta cells in the pancreas that secrete insulin. Does not know the real reason for how to begin to influence the body's immune system, but studies suggest that genetic predisposition and infection with certain viruses may Be causing the lack of efficiency of the body's immune system.
Genetic factors
Diabetes, which affects the very young and needs to insulin in the treatment may not be due to genetics.Statistics have shown that worked during the last thirty years, a significant increase in the incidence of type I diabetes in some European countries and the United States of America. Had Genetic factors are the sole cause of the first type of sugar, the increase in the number of cases will take at least 400 years.
Virus
Researchers believe that the incidence of certain viruses such as those that cause rubella , And mumps(mumps ), And other viruses of the genus "Cox Sacchi Coxsackie ", Especially in people who have a genetic predisposition, may be a cause of type I diabetes.
These viruses violently attacking the beta cells in the pancreas to secrete insulin and destroy. The structure of these viruses similar structure of proteins in beta cells in the pancreas and works to deceive the immune system (the people who have their immune systems gallery and genetically) calculated the immune system error that beta cells are virus particles and the formation of antibodies to address to beta cells, rather than addressing virus and thus destroys the beta cells by antibodies directed the wrong direction due to viruses. The attack viruses and destroying beta cells directly and lead to rapid insulin deficiency, or lead to the gradual loss of beta cell function and diabetes occurs after several years of virus infection.
This type accounts for only 5-10% of diabetics.
Different races or strains
There are significant differences between the people in the incidence of type I diabetes. It is more common in people of northern Europe and some parts of the Mediterranean (such as Sardinia), and less common among Asians and African-Americans. In America, it was found that blacks with type I diabetes more likely to die of the equivalent of 50% of white people, and it may be reason for this low medical care among blacks (Rennert et al., 1999).
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types of diabetes