When the substance is inhaled, it is exposed to nasal or oral membranes, pharynx, trachea, bronchial tubes, air sacs, and air sacs.
The lung has a surface absorption area of about 70 square meters, which is larger than the surface of the micro-absorbent. However, lung and associated airways have been adopted to prevent access to compounds described to high-absorbent peripheral lung surfaces. The device is designed to prevent access to the molecular material. However, if the substances reach the peripheral region of the lung, the absorption will be very effective. Both the particle size and the speed of application control the permeability of the inhaled material to the airway space. The optimum size of the particles so that they can penetrate the airway in depth is about 3-5 micrometers and will emulate the large particles of the upper airway.
Most inhalation devices can deliver approximately 10% of the applied dose to the lower respiratory tract. Many methods have been developed to increase pulmonary delivery. The drug was given to 21% when the pressurized metered dose inhaler was used. Despite these advantages, the administration of pneumonia remains ineffective.
The systemic availability of inhaled drugs can be inhibited by first pulmonary embolism.
The lung contains many drug metabolism enzymes that contain mixtures of the functions of oxidase, monosamine and esterase. Several models of animals, especially rat, rabbit and dog, are used in the study of drug inhalation.
The lung has a surface absorption area of about 70 square meters, which is larger than the surface of the micro-absorbent. However, lung and associated airways have been adopted to prevent access to compounds described to high-absorbent peripheral lung surfaces. The device is designed to prevent access to the molecular material. However, if the substances reach the peripheral region of the lung, the absorption will be very effective. Both the particle size and the speed of application control the permeability of the inhaled material to the airway space. The optimum size of the particles so that they can penetrate the airway in depth is about 3-5 micrometers and will emulate the large particles of the upper airway.
Most inhalation devices can deliver approximately 10% of the applied dose to the lower respiratory tract. Many methods have been developed to increase pulmonary delivery. The drug was given to 21% when the pressurized metered dose inhaler was used. Despite these advantages, the administration of pneumonia remains ineffective.
The systemic availability of inhaled drugs can be inhibited by first pulmonary embolism.
The lung contains many drug metabolism enzymes that contain mixtures of the functions of oxidase, monosamine and esterase. Several models of animals, especially rat, rabbit and dog, are used in the study of drug inhalation.
