hydrochlorothiazide work by.. decrease na reabsorption at early distal tubules

hydrochlorothiazide work by:

• a- increase hco3 secretion
• b- increase k reabsorption at early distal tubules
• c- decrease na reabsorption at early distal tubules***
• d- prevent na reabsorption at loop of henle

Hydrochlorothiazide works by c) decreasing sodium reabsorption at the early distal tubules.

Hydrochlorothiazide is a thiazide diuretic, which means that it works by blocking the sodium-chloride cotransporter in the early distal tubules. This cotransporter is responsible for reabsorbing sodium and chloride from the urine back into the blood. When hydrochlorothiazide blocks this cotransporter, more sodium and chloride are excreted in the urine, which leads to an increase in urine output.

The other answer choices are incorrect:

• Hydrochlorothiazide does not increase bicarbonate secretion.
• Hydrochlorothiazide does not increase potassium reabsorption at the early distal tubules.
• Hydrochlorothiazide does not prevent sodium reabsorption at the loop of Henle.

Hydrochlorothiazide is commonly used to treat high blood pressure and edema (fluid retention). It can also be used to treat other conditions, such as heart failure and liver failure.