Thrombocene and lecotrains are prostaglandins and are created or installed in cells of arachidonic acid.
Although their functions correspond to the functions of the prostrogendins and their similarity to the structure, they do not contain the basic structure of brosinok.
Thermoboxanas can be derived from prostaglandins by synthesis and biochemistry.
It causes the accumulation of blood clots and contractions of the arteries and is considered an important organization for the work of polyunsaturated fatty acids.
Lycotriins are called because they are present in the white globules and in their triangular structure.
It is an effective holding of pulmonary people and plays an important role in allergic reactions.
A: Thromboxan B2: It is a blood vessel and pulmonary people, and it is used to collect blood clots.
L-cotraine C4: It is 100 to 1000 times more effective than histamine or prostaglandins for its effect on airway passage in the pulmonary artery.
Other hormones
Hormones, which differ in structure from the hormones referred to above, such as melatonin, found in the cone or coniferous gland, can be considered as endol derivatives.
Prostaglandins are metabolites of arachidonic acid, obtained from membrane phospholipids by the action of phospholipases (several existing subtypes). Liposoluble molecules intended for secretion in the extracellular medium, these are cytokines that play important roles in living organisms. Indeed, prostaglandins are paracrine and autocrine signaling agents that activate many GPCRs (membrane-bound 7-segment membrane receptors coupled to G proteins). Each prostaglandin has 20 carbon atoms including a ring with 5 carbon atoms. They are chemical mediators that have various physiological effects, contributing in particular to the development of several inflammatory manifestations, vasodilatation and pain.
Prostaglandins belong to the class of prostanoids, which also contains thromboxanes and prostacyclins. Prostanoids are themselves a sub-category of eicosanoids (combining prostanoids and leukotrienes).
History and nomenclature:
The name prostaglandin (PG) comes from prostate. Prostaglandin was first isolated in seminal fluid in 1935 by Swedish physiologist Ulf von Euler1 and independently by W.W. Goldblatt2. It was believed that it was secreted by the prostate (in fact the prostaglandins are produced by the seminal vesicles). It has been shown later that several other tissues produce prostaglandins which have varied effects.
In nomenclature, we denote PG the series - E, F, Alpha or I - the class - 1,2 or 3 - followed by isomerism if it is necessary - Trans or Cis.
Biochemistry:
Prostaglandins are found in virtually all tissues and organs. They are autocrine and paracrine lipid mediators that act on platelets, endothelium, uterus and mast cells, among other things. They are synthesized in the cell from essential fatty acids:
- di-homo-gamma-linolenic acid (C20: 3 (n-6)) leads to the prostaglandins of the index series.
arachidonic acid (AA, C20: 4 (n-6)) gives the prostaglandins of the index series.
- Eicosapentaenoic acid (EPA, C20: 5 (n-3)) leads to the prostaglandins of the index series.
The production of prostaglandins of the index series requires arachidonic acid. It can be provided by the diet, but is also produced endogenously by the body, by phospholipase A2 degradation of phosphatidylcholine molecules (a membrane phospholipid). Arachidonic acid then undergoes the action of cyclooxygenase or that of lipoxygenase. Cyclooxygenase will lead to the formation of thromboxane, prostacyclin (also called prostaglandin I2) and prostaglandins D, E and F. Lipoxygenase is active in leucocytes and macrophages and forms leukotrienes.
Although their functions correspond to the functions of the prostrogendins and their similarity to the structure, they do not contain the basic structure of brosinok.
Thermoboxanas can be derived from prostaglandins by synthesis and biochemistry.
It causes the accumulation of blood clots and contractions of the arteries and is considered an important organization for the work of polyunsaturated fatty acids.
Lycotriins are called because they are present in the white globules and in their triangular structure.
It is an effective holding of pulmonary people and plays an important role in allergic reactions.
A: Thromboxan B2: It is a blood vessel and pulmonary people, and it is used to collect blood clots.
L-cotraine C4: It is 100 to 1000 times more effective than histamine or prostaglandins for its effect on airway passage in the pulmonary artery.
Other hormones
Hormones, which differ in structure from the hormones referred to above, such as melatonin, found in the cone or coniferous gland, can be considered as endol derivatives.
Prostaglandins are metabolites of arachidonic acid, obtained from membrane phospholipids by the action of phospholipases (several existing subtypes). Liposoluble molecules intended for secretion in the extracellular medium, these are cytokines that play important roles in living organisms. Indeed, prostaglandins are paracrine and autocrine signaling agents that activate many GPCRs (membrane-bound 7-segment membrane receptors coupled to G proteins). Each prostaglandin has 20 carbon atoms including a ring with 5 carbon atoms. They are chemical mediators that have various physiological effects, contributing in particular to the development of several inflammatory manifestations, vasodilatation and pain.
Prostaglandins belong to the class of prostanoids, which also contains thromboxanes and prostacyclins. Prostanoids are themselves a sub-category of eicosanoids (combining prostanoids and leukotrienes).
History and nomenclature:
The name prostaglandin (PG) comes from prostate. Prostaglandin was first isolated in seminal fluid in 1935 by Swedish physiologist Ulf von Euler1 and independently by W.W. Goldblatt2. It was believed that it was secreted by the prostate (in fact the prostaglandins are produced by the seminal vesicles). It has been shown later that several other tissues produce prostaglandins which have varied effects.
In nomenclature, we denote PG the series - E, F, Alpha or I - the class - 1,2 or 3 - followed by isomerism if it is necessary - Trans or Cis.
Biochemistry:
Prostaglandins are found in virtually all tissues and organs. They are autocrine and paracrine lipid mediators that act on platelets, endothelium, uterus and mast cells, among other things. They are synthesized in the cell from essential fatty acids:
- di-homo-gamma-linolenic acid (C20: 3 (n-6)) leads to the prostaglandins of the index series.
arachidonic acid (AA, C20: 4 (n-6)) gives the prostaglandins of the index series.
- Eicosapentaenoic acid (EPA, C20: 5 (n-3)) leads to the prostaglandins of the index series.
The production of prostaglandins of the index series requires arachidonic acid. It can be provided by the diet, but is also produced endogenously by the body, by phospholipase A2 degradation of phosphatidylcholine molecules (a membrane phospholipid). Arachidonic acid then undergoes the action of cyclooxygenase or that of lipoxygenase. Cyclooxygenase will lead to the formation of thromboxane, prostacyclin (also called prostaglandin I2) and prostaglandins D, E and F. Lipoxygenase is active in leucocytes and macrophages and forms leukotrienes.
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