Sideroblastic.a seen in all except?
- a. Lead poisoning.
- b. Alcohol.
- c. Aspirin.
- d. Chloramphenicol.
The option most likely not associated with sideroblastic anemia is: c. Aspirin
Here's why:
Sideroblastic anemia:
This is a group of blood disorders characterized by the ineffective production of hemoglobin due to impaired iron utilization in red blood cell precursors. This leads to anemia with characteristic ringed sideroblasts (iron deposits) in the bone marrow.
Causes:
Various factors can cause sideroblastic anemia, including genetic mutations, nutritional deficiencies (vitamin B6, copper), and exposure to certain toxins or medications.
Option analysis:
a. Lead poisoning:
Lead is a well-known cause of sideroblastic anemia through its interference with heme synthesis.
b. Alcohol:
Chronic alcohol abuse can disrupt iron metabolism and contribute to sideroblastic anemia.
d. Chloramphenicol:
This antibiotic can inhibit mitochondrial protein synthesis, leading to sideroblastic anemia as a side effect.
c. Aspirin:
While aspirin can cause other blood cell abnormalities, it's not typically associated with sideroblastic anemia.
Therefore, based on the typical causes of sideroblastic anemia, aspirin is the least likely option among the choices provided.
It's important to note that medical diagnoses should be made by qualified healthcare professionals based on individual patient assessments and investigations. This information is for educational purposes only and should not be used as a substitute for professional medical advice.
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Hematology