Monday, February 20, 2023

Cases to use more than one antibiotic Antibiotic Combination.. The foundations of the use of antibiotics together



Cases to use more than one antibiotic Antibiotic Combination:

1- in cases of infection by more than one type of bacteria (infection mixture - Mixed infection).
2- to expand the range of antibiotic.
3- to reduce the toxicity of certain antibiotics highly toxic.
4- to reduce microbial immune to the antibiotic per Bacterial Resistance

The foundations of the use of antibiotics together:

1- can be used successfully fought with deadly Bactericidal + Bactericidal.
Cohesion example Penicillin + Streptomycin And Ampicillin + Gentamicin.

2- can be used stand growth and reproduction with the position of growth and reproduction + Bacteriostatic In some cases.
Cohesion example Tetracyclines + Macrolides Macrolides + Sulphonamides.

3- You can not use the growth and reproduction position with deadly bacteria Bactericidal   Bacteriostatic X.

Antagonism Antagonism Example Tetracycline + Penicillin X.

The most common examples of poor or frequent use of antibiotics are:


  • Respiratory diseases in children should not be treated with antibiotics unless there is a bacterial infection.
  • When children with tubal tubes have an infection in the ear they should take antibiotics in the form of drops and put them in the ear directly to the infection, and keep away from antibiotics taken orally; to avoid side effects
  • External ear infection should be treated with antibiotics in the form of drops and not by mouth.
  • Sinusitis should not be treated with antibiotics because it is often caused by viruses, even if caused by bacteria. Antibiotics should only be used in abnormal conditions. Sinusitis is often cured without treatment.
  • The conjunctivitis virus should not be treated with antibiotics. In bacterial conjunctivitis only, they should be used.
  • Older people often have bacteria in their urine, and are determined by a routine urine test.
  • A person who has symptoms of urinary tract infection does not use antibiotics unless the doctor is consulted.
  • Eczema most of the time should not be treated with antibiotics. Dry skin and its symptoms can be treated with moisturizers.
  • The use of antibiotics in the treatment of wounds resulting from the process does not reduce the rate of infection compared to the ointments never.

Why does taking lots of antibiotics increase the risk of antibiotic resistance?

Anytime antibiotics are used, they can contribute to antimicrobial resistance. This is because increases in antimicrobial resistance are driven by a combination of germs exposed to antibiotics, the spread of those germs, and their mechanisms of resistance.

What are the symptoms of too many antibiotics?

Common side effects of antibiotics include nausea, diarrhea, and stomach pain. Sometimes these symptoms can lead to dehydration and other problems. Ask your doctor about drug interactions and potential side effects of antibiotics.

Can too many antibiotics cause infection?

This leads to to strains that can cause fatal infections. While specialists are making strides to preserve the effectiveness of antibiotics and to slow potential infections through better policy, the overuse of antibiotics continues to have severe health consequences for the U.S. and around the world.

What are 2 different reasons that they use antibiotics on farms?

Antibiotics are used widely in livestock production for control, prevention, and treatment of disease, and for “production purposes” such as growth promotion.

How does taking a combination of drugs avoid the development of antibiotic resistance?

This is another possible benefit of combination therapy: Combining antibiotics might enable the reduction of the concentration of potentially toxic antibiotics, while still minimizing the likelihood of resistance evolution.

Why combination of drugs is desirable for treatment of some diseases?

One major benefit of combination therapies is that they reduce development of drug resistance since a pathogen or tumor is less likely to have resistance to multiple drugs simultaneously.

Can I take amoxicillin and ciprofloxacin together?

Interactions between your drugs


No interactions were found between amoxicillin and Cipro XR. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Can I take 2 antibiotics closer together?

There's an increased risk of side effects if you take 2 doses closer together than recommended. Accidentally taking 1 extra dose of your antibiotic is unlikely to cause you any serious harm. But it will increase your chances of getting side effects, such as pain in your stomach, diarrhoea, and feeling or being sick.

What is synergistic effect of antibiotic?

A synergistic effect between peptides and traditional antibiotics can be a potential option to improve the effectiveness of antimicrobial agents, increase bacterial killing and prevent the emergence of the development of both antibiotic and peptide resistance.

What are the effects of synergism?

Definition: Effects when chemical substances or biological structures interact resulting in an overall effect that is greater than the sum of individual effects of any of them.

Can synergism have negative effects?

An interaction between two or more drugs that causes the total effect of the drugs to be greater than the sum of the individual effects of each drug. A synergistic effect can be beneficial or harmful.

What are the advantages of antibiotic combination therapy?

Combinations of AGAs such as gentamicin can expand the scope of clinical treatment, accelerate bacterial clearance, and improve antibiotic resistance, especially the because of the synergistic antibacterial effects with β-lactam antibiotics (Le et al., 2011; Rhodes et al., 2017).

Why is a combination of different antibiotics used in the case of a severe community acquired pneumonia?

Different factors may explain the superiority of combination therapy compared with monotherapy for the treatment of patients with severe CAP. Combination therapy has a better coverage of atypical microorganisms in polymicrobial CAP, including both Chlamydia pneumonia and Mycoplasma pneumonia.

What happens when more and more antibiotics are used?

Taking antibiotics too often or for the wrong reasons can change bacteria so much that antibiotics don't work against them. This is called bacterial resistance or antibiotic resistance. Some bacteria are now resistant to even the most powerful antibiotics available. Antibiotic resistance is a growing problem.

What is an example of antibiotic synergism?

For example, synergistic effects have been demonstrated for double and triple antibiotic combinations including an aminoglycoside, an anti-pseudomonal beta-lactam, colistin, a fluoroquinolone, a macrolide, or rifampin against multidrug-resistant Pseudomonas spp.

Can I take 3 different antibiotics together?

"Three antibiotics can change the dynamic," she said. "Not many scientists realize that three-drug combinations can have really beneficial effects that they would not have predicted even by studying all pairs of the antibiotics together." Different classes of antibiotics use different mechanisms to fight bacteria.

What is combination of two antibiotics?

A combination antibiotic is one in which two ingredients are added together for additional therapeutic effect. One or both ingredients may be antibiotics. Antibiotic combinations are increasingly important because of antimicrobial resistance.

Can two antibiotics be used together?

Two antibiotics may be synergistic with one another. In the initial emergency treatment of seriously ill patients where the establishment of an etiological diagnosis and appropriate antibiotic sensitivity tests may be delayed, two or more drugs may properly be used as "insurance."

When two antibiotics are used together for a treatment and their combined effect is better than their individual effects they are said to be?

In medicine, describes the interaction of two or more drugs when their combined effect is greater than the sum of the effects seen when each drug is given alone.

What is the reason for combined use of antibiotics?

Reasons for using combination therapy


Broadening antibacterial spectrum. Use of more than one agent broadens the antibacterial spectrum of the empirical therapy and thus ensures that at least one agent will cover the infecting organism.