Variation rate of insulin absorption from one place to another under the skin
There are many types of insulin, and they all act differently in the body according to their respective chemical structures. But did you know that the same type of insulin can have varying absorption rates depending on the injection site?
There are four approved sites for the subcutaneous injection of insulin:
- Abdomen: You can do an injection anywhere outside a two-centimetre (or two-finger) radius around the navel.
- Thighs: It is recommended to use the outside of the thighs and to keep at least a one-hand distance from the knee or hip.
- Upper buttocks
- Back of the arms: If you have a hard time reaching the back of your arm, try leaning your arm on the back of a chair and pivoting slightly.
How does the insulin absorption rate fluctuate?
Remember that no matter what injection site you use out of these four, the quantity of insulin that is absorbed remains the same. The absorption rate is the only aspect that can vary from one site to the other. This is important to know when choosing an injection site for certain types of rapid-acting insulin taken at mealtime. The abdomen is generally the subcutaneous injection site with the fastest absorption rate. The arms have an average absorption rate, while the buttocks and thighs have a slower absorption rate.
Absorption rate fluctuations vary from one person to the other, and depending on the type of insulin. They seem to be more frequent with rapid-acting types of insulin and minor with the latest types.
Insulin absorption rate is known to be a lot quicker when the insulin is injected in a muscle than when injected in fat tissue. It is important that you use the right type and length of needle for your build.
Also, remember that any of the following can increase the insulin absorption rate:
- A massage over the injection site
- A hot bath
- Physical activity that solicits the body part used for the injection
- Things to consider for your next injection
Beware! A higher insulin absorption rate also means a greater risk of hypoglycemia. So, you need to remain vigilant and take this factor into consideration when choosing your injection site. For example, if you’re planning to play tennis after a meal, avoid injecting your insulin into your arms.
What destroys the cells that make insulin?
In T1D, immune cells called T lymphocytes attack and destroy insulin-secreting pancreatic beta cells and the pancreas stops producing insulin, the hormone that controls blood sugar levels.
What is the best exercise for insulin resistance?
Any type of physical activity has the potential to make your insulin work better, and combining aerobic activities — such as brisk walking, swimming, and cycling — with resistance training, or weight training, appears to have the greatest effect.
Which organ is most sensitive to insulin?
The brain as an insulin-sensitive metabolic organ.
Which tissue is more insulin sensitive?
Individuals with normal weight and normal glucose tolerance are highly sensitive to insulin in skeletal muscle, adipose tissue and liver (2, 3, 4), whereas obese individuals and individuals with type 2 diabetes are insulin resistant (4, 5, 6).
Does insulin absorb faster in the abdomen?
This is important to know when choosing an injection site for certain types of rapid-acting insulin taken at mealtime. The abdomen is generally the subcutaneous injection site with the fastest absorption rate. The arms have an average absorption rate, while the buttocks and thighs have a slower absorption rate.
How can I absorb insulin faster?
Massage the area. Anything that increases blood flow to the skin surface will accelerate the absorption of insulin. Massage is one such thing. Rubbing the area for several minutes within 15 minutes after injecting will help the insulin reach the bloodstream just a bit quicker.
Can you give insulin in the arm?
A person can administer insulin injections into the abdomen, upper arm, thigh, lower back, hips, or buttocks. Take into account comfort, as injections into some sites can cause pain. Be sure to inject into a pinch of tissue and consider the different methods for injection at each site.
What causes cells to not absorb insulin?
What Causes Insulin Resistance? It isn't clear exactly what causes insulin resistance, but a family history of type 2 diabetes, being overweight (especially around the waist), and being inactive all can raise the risk. You do not have to be overweight to have insulin resistance.
What factors affect absorption?
Drug absorption depends on the lipid solubility of the drug, its formulation and the route of administration. A drug needs to be lipid soluble to penetrate membranes unless there is an active transport system or it is so small that it can pass through the aqueous channels in the membrane.
What factors increase absorption?
Factors that may improve nutrient absorption include a healthy diet, regular exercise and timing and method of supplement intake.
Can you inject insulin in your inner thigh?
But while the needle for insulin therapy is becoming shorter, it is possible to inject insulin at the inner thigh site. inject insulin at inner thigh site is the intervention arm.
Can I inject insulin into my thigh?
You can rotate to different areas of your abdomen, keeping injection sites about an inch apart. Or you can inject insulin into other parts of your body, including your thigh, arm, and buttocks.
Does insulin get absorb through skin?
Insulin can be absorbed through the skin, so wash your hands thoroughly after handling any insulin-holding device.” Is this true? The part about the insulin and skin, I mean, not the part about the disposal regs.
Which is the site with the fastest rate of insulin absorption?
As insulin is absorbed fastest from the abdomen,slower from the arm followed by thighs and buttocks, choice of injection region may for many insulin preparations influence the metabolic response to insulin .
Is insulin in the thigh better than in the abdomen?
The belly is the best place to inject insulin. This is because the belly area can absorb insulin most consistently. The front of the thighs. Insulin usually is absorbed more slowly from this site.
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