1 - ease of administration - where the administration of sulfonylureas drugs by mouth is no doubt that it is easier and less expensive than giving insulin injections.
2 - Give sulfonylureas drugs by mouth stimulates the secretion of insulin from the beta cells in the pancreas and is therefore similar physiological scientific terms that insulin released from the pancreas by these drugs first reaches the liver and affect the exit of glucose from the liver. In contrast, the insulin given by injection will result in the accumulation of insulin in peripheral tissues before it reaches the liver.
3 - sulfonylureas drugs are less likely to cause insulin sensitivity because of insulin that is given by injection private extracted from animal source or persons who have no antibodies to insulin.
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sulfonylureas