vitamin k is antidote for.. warafarin

vitamin k is antidote for:
a- warafarin***
b- aspirin.
c-………..
I choused warafarin because vit k more specific for it than aspirin But both warafarin and aspirin are right.

Warfarin is anticoagulant, used to prevent blood clotting, especially in areas where blood flows slowly, such as veins in the legs and pelvis.
Blood clots that form in these areas may break down and travel with the bloodstream and settle in the lungs, blocking the pulmonary blood vessels and causing death. Warfarin is also used to reduce the risk of heart thrombosis in people with atrial fibrillation or those undergoing artificial heart valve transplantation.
These clots may reach the brain and cause a CVA (Cerebrovascular accident).
Warfarin is a commonly used drug. And requires regular monitoring of its use, in order to ensure an appropriate maintenance dose of this drug.
Since the full positive effects of warfarin appear only after 2 to 3 days, the patient is often given a fast-acting anticoagulant such as heparin to supplement the effect of warfarin at the start of treatment.
The most serious side effect of warfarin, like all anticoagulants, is the risk of excessive bleeding, usually caused by overdose.

The warfarin was discovered in 1940. In 1920, cattle in North America and Canada were infected with a fatal hemorrhage. The cause of the disease was found in a moldy stock of sweet clover in which the hemorrhagic agent was a mystery until 1940, Prothrombin (the main substance from which anticoagulant agents are produced), namely 3.3'-methylenebis- (4-hydroxycoumarin), and Warfarin was coined by the Wisconsin Alumni Research Foundation (WIS) WARF and subsequent arin of coumarin (coumarin), then warfarin appeared commercially for the first time in 1 year 948, which has been marketed as a rodent and is still being used for this purpose until now. After a few years of marketing, it has been shown to be effective in preventing blood clotting in many cases. Warfarin was approved as a drug in 1954 and is still commonly used today.

Uses:

Warfarin is used to reduce blood mileage to coagulation as primary protection in certain conditions such as atrial fibrillation, artificial heart valves, phospholipid antibody syndrome or sometimes heart attacks. It is also used as secondary prevention to prevent further clot formation in patients with thrombosis Such as deep venous thrombosis, or pulmonary embolism.

Pharmaceutical Information:

Wavarin is made in the form of oral tablets with multiple doses (1 mg, 2 mg, 2.5 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7.5 mg, 10 mg). Blood susceptibility to coagulation. This medicine should be taken at the same times of the day regularly and can be taken on an empty stomach or after eating, but it is recommended to be taken after food. If it causes irritation or stomach upset, the activity starts within 24 - 48 hours, but the full positive effects of warfarin are not The effect of warfarin is monitored by the PT test. The results of the prothrombin time test are usually given by calculating this time compared to the international standard (INR-International Normalized Ratio) ), Where INR normal values ​​range from 0.8 to 1.2, and are usually controlled The risk of bleeding, whether it is externally bleeding from the nose or life-threatening, such as internal hemorrhage in the brain or the heart, for example, but if the INR blood flow falls below the required limit This means that the dose of warfarin is not enough to protect the patient from thrombophlebitis and should be increased.

Notes:

The use of warfarin may have some serious side effects such as: appetite disorder, bleeding of the gums after brushing, menstrual bleeding, diarrhea or vomiting, fever.

However, there are other side effects that require immediate medical attention such as: severe bleeding, including more frequent menstrual bleeding, red or brown urine, black or bloody stools, severe headache, stomach pain, joint pain or discomfort Swelling, bloody vomit or vomiting of coffee-like substance, insomnia, bruising without injury, dizziness or weakness, vision changes.

It is recommended to take vitamin K approximately the same amount every day, and green leafy foods containing vitamin K (clover, asparagus, broccoli, Brussels sprouts, cabbage, cabbage, turnip, lettuce, spinach, watercress).

Some medications may interfere with warfarin, so you may need to adjust your dose or perform certain tests when using these medications: antibiotics (azithromycin, erythromycin, tetracycline), nonsteroidal anti-inflammatory drugs (acetylsalicylic acid, silicocip), paracetamol Depression (fluoxetine, paroxetine, sertraline), stomach ulcers (cimetidine, omeprazole, ranitidine), lipid lowering drugs (statins and simvastatin), antifungal drugs (itraconazole, fluconazole).

Some foods and dietary supplements can interact with warfarin, such as: cranberries, garlic, alcohol, ginseng, ginkopilbia, mite sweat.

It is forbidden to take warfarin during pregnancy (class X). Taking the medicine early in pregnancy can cause fetal abnormalities, and taking the medicine as the baby approaches, can cause severe bleeding in the mother.

It can be taken in the course of lactation although it is transferred to breast milk, but when taking regular doses, there should be no negative effects on infants.

The treatment of warfarin is prevented in the following cases: bleeding (eg, active stomach ulcers, digestive bleeding), hemophilia, thrombocytopenia purpura, leukemia, patients who recently underwent surgery, patients planning surgery soon, ascorbic acid deficiency , High and uncontrolled hypertension.