Ondansetron HCL is used for.. Anti-emetic

Ondansetron HCL is used for:
a- Hypertension.
b- Angina pectoris.
c- Prophylaxis of migraine .
d- Anti-emetic ***

It is used as anti-emetic with patients receiving cytotoxics due
 to its serotonin antagonism.
Ondansetron is [Zofran 2 , 4 mg. Tab & Amp.]

An antiemetic is a medicine that acts against vomiting and nausea. Antiemetics are typically used to treat motion sickness (motion sickness) and the side effects of certain analgesic opiates and cancer chemotherapy.

Main antiemetics:

+ Dopamine antagonists:
- domperidone
- haloperidol, chlorpromazine
- metoclopramide
- olanzapine
- Prochlorperazine

+ Antihistamines H1:
- cyclizine
- diphenhydramine
- dimenhydrinate

+ Synthetic glucocorticoids:
- prednisone
- prednisolone
- methylprednisolone
- dexamethasone
- betamethasone

+ 5HT3 Antagonists or Setrons:
- dolasetron
- granisetron
- ondansetron
- tropisetron
- Palonosetron

+ Antagonist of NK1 receptors (tachykinin receptors):
- Aprepitant and his prodrug, the fosaprepitant
- netupitant
- rolapitant

+ Cannabinoids:
- cannabis
- marinol
- dronabinol
- nabilone

Statistics:
In the United States, the most prescribed anti-emetics in 2013 are metoclopramide, prochlorperazine, promethazine, droperidol and ondansetron.
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